Evidence map›Paper›PMID 35135057›Full record

ReviewJournal of stroke2022

Hypertriglyceridemia: A Neglected Risk Factor for Ischemic Stroke?

Hai-Jie Liang, Qing-Yi Zhang, Yi-Tong Hu, Guo-Qing Liu, Rong Qi

Open access · diamondAbstract readReview
In one paragraph

Review in Journal of stroke, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
30citing papers in PubMed, 2 pooled it
8.9field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

30 citing papers in PubMed, 2 syntheses or guidelines pooled it, 55 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Hai-Jie LiangDepartment of Pharmacology, School of Basic Medical Sciences, Beijing, China.
Qing-Yi ZhangDepartment of Pharmacology, School of Basic Medical Sciences, Beijing, China.
Yi-Tong HuDepartment of Pharmacology, School of Basic Medical Sciences, Beijing, China.
Guo-Qing LiuKey Laboratory of Molecular Cardiovascular Sciences, Ministry of Education, Beijing, China.
Rong QiDepartment of Pharmacology, School of Basic Medical Sciences, Beijing, China.
Ministry of Education of the People's Republic of China · CN

Funding

National Key Research and Development Program 2019YFE0113500National Natural Science Foundation of China 81770268National Natural Science Foundation of China U1803125
6 · The paper itself

Abstract

Hypertriglyceridemia is caused by defects in triglyceride metabolism and generally manifests as abnormally high plasma triglyceride levels. Although the role of hypertriglyceridemia may not draw as much attention as that of plasma cholesterol in stroke, plasma triglycerides, especially nonfasting triglycerides, are thought to be correlated with the risk of ischemic stroke. Hypertriglyceridemia may increase the risk of ischemic stroke by promoting atherosclerosis and thrombosis and increasing blood viscosity. Moreover, hypertriglyceridemia may have some protective effects in patients who have already suffered a stroke via unclear mechanisms. Therefore, further studies are needed to elucidate the role of hypertriglyceridemia in the development and prognosis of ischemic stroke.

Indexed as

HypertriglyceridemiaIncidenceIschemic strokePrognosis

Identifiers

PMID35135057
PMCPMC8829486
OpenAlexW4210436487

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.