ArticleAge and ageing2022
Risk of progression to diabetes and mortality in older people with prediabetes: The English longitudinal study on ageing.
Article in Age and ageing, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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14 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.
- Risk factors for progression to type 2 diabetes in prediabetes: a systematic review and meta-analysis.BMC public health · 2025Pooled it
- A novel nutritional index for hypertension risk and prediction: Cross-sectional, prospective, and trajectory evidence from the English Longitudinal Study of Ageing.The Journal of international medical research · 2026Article
- Predicting pre-diabetes progression: a systematic review and meta-analysis.BMJ nutrition, prevention & health · 2026Article
- Evaluation of Capillary Blood Glucose and Chinese Diabetes Risk Score in Screening for Diabetes and Prediabetes Among Elderly Chinese Population: A Cross-Sectional Study.Clinical interventions in aging · 2026Article
- Global, regional, and national burden of diabetes and kidney diseases, 1990-2021: a trend and health inequality analyses based on the Global Burden of Disease Study 2021.Renal failure · 2025Article
- Incidence and predictors of type 2 diabetes mellitus in a population-based cohort study in Abu Dhabi.Scientific reports · 2025Article
- Development of 3-Year Risk Prediction Model for Type 2 Diabetes in Older Adults with Prediabetes - China, 2019-2022.China CDC weekly · 2025Article
- Dynapenic abdominal obesity and incident multimorbidity: findings from the English longitudinal study on ageing.Aging clinical and experimental research · 2023Article
- A framework of biomarkers for vascular aging: a consensus statement by the Aging Biomarker Consortium.Life medicine · 2023Article
- Association of phenotypic age acceleration with all-cause and cardiovascular disease-specific mortality in individuals with prediabetes and diabetes: results from the NHANES study.Journal of endocrinological investigation · 2023Article
- Multimorbidity increases the risk of dementia: a 15 year follow-up of the SHARE study.Age and ageing · 2023Article
- Risk of Death Associated With Reversion From Prediabetes to Normoglycemia and the Role of Modifiable Risk Factors.JAMA network open · 2023Article
- Top POEMs of 2022 for choosing wisely in practice.Canadian family physician Medecin de famille canadien · 2023Article
- Differences in the impact of impaired glucose status on clinical outcomes in younger and older adults: Over a decade of follow-up in the Tehran lipid and glucose study.Frontiers in cardiovascular medicine · 2022Article
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Authors and funding
8 authors at 5 institutions in 2 countries.
Funding
Abstract
aimsPrediabetes is used to identify people at increased risk for diabetes. However, the importance of prediabetes in older populations is still poorly explored. Therefore, we aimed to investigate the prevalence of prediabetes, based on either glycated haemoglobin (HbA1c) levels or fasting glucose (FG) levels, or both and the progression of prediabetes to diabetes or to mortality in older participants of the English Longitudinal Study on Ageing. MATERIALS AND
methodsPrediabetes was categorized based on HbA1c levels (5.7%-6.4%) and/or FG levels (5.6-7.0 mmol/L). Information regarding mortality and incident diabetes were recorded during follow-up period of 10 years.
resultsIn 2027 participants (mean age: 70.6 years, 55.2% females), the prevalence of prediabetes ranged between 5.9% and 31.1%. Over 8 years of follow-up, 189 participants (5.4% of the initial population) developed diabetes and 606 (17.4%) died. Among 1,403 people with HbA1c at the baseline <5.7%, 33 developed diabetes and 138 died; in contrast, among 479 participants with a diagnosis of prediabetes using a value of HbA1c between 5.7% and 6.4%, 62 developed diabetes and 56 died. Similarly, among 1,657 people with normal values of FG at baseline 60 had a diagnosis of diabetes during follow-up and 163 died, compared to 225 with FG between 5.6 mmol/L and 7.0 mmol/L in which 35 developed diabetes and 31 died.
conclusionThe prevalence of prediabetes in older adults is high, but the progression from prediabetes to diabetes is uncommon, whereas the regression to normoglycemia or the progression to death was more frequent.
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