ArticleNature2022
Automated iterative Csp
Article in Nature, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 42 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
42 citing papers in PubMed.
- "MIDA masking" of boronic acid therapeutics for enhanced stability and economy.RSC chemical biology · 2026Article
- Editor's pick: Excelsior Sciences.Nature biotechnology · 2026Article
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- Mix-and-match synthesis of 3D small molecules.Nature · 2026Article
- Topology-controlled dynamic conjugated oligomers from tetra-arylsubstituted alkene building blocks.Nature communications · 2026Article
- Illuminating the Interface of Blocc Chemistry and Data Science: Maximizing Function with ML-Guided Discovery and a Digital Molecule Maker.Journal of chemical education · 2026Article
- Article
- Illuminating the Interface of Blocc Chemistry and Data Science: An Introduction to K‑Nearest Neighbor Analysis and K‑Medoids Clustering.Journal of chemical education · 2025Article
- 1,2-Migratory ring expansion of a BN-naphthalene.Organic & biomolecular chemistry · 2025Article
- Automated Iterative N─C and C─C Bond Formation.Angewandte Chemie (International ed. in English) · 2025Article
- Rethinking carbanion chemistry from donor substituents to weakly coordinating carbanions.Nature reviews. Chemistry · 2025Review
- Potential of Boronic Acid Derivatization and Activity in Agrochemical Discovery.Molecules (Basel, Switzerland) · 2025Review
- Atom-by-Atom Iterative Synthetic Logic: Laying the Foundation for Programmable Automated Construction of Small Organic Molecules.ACS central science · 2025Review
- Size-Programmable Matteson-Type Annulation: Construction of Spirocycles from Simple Cyclic Ketones.Angewandte Chemie (International ed. in English) · 2025Article
- What I Learned from Analyzing Accurate Mass Data of 3000 Supporting Information Files.Organic letters · 2025Article
- Syntheses of Marine Natural Products via Matteson Homologations and Related Processes.Marine drugs · 2025Review
- Article
- Reaction blueprints and logical control flow for parallelized chiral synthesis in the Chemputer.Nature communications · 2024Article
- Article
- Minimizing higher-order aggregation maximizes iron mobilization by small molecules.Nature chemical biology · 2024Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
17 authors.
Funding
Abstract
Fully automated synthetic chemistry would substantially change the field by providing broad on-demand access to small molecules. However, the reactions that can be run autonomously are still limited. Automating the stereospecific assembly of Csp
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.