Evidence map›Paper›PMID 35134802›Full record

ArticleCerebrovascular diseases extra2022

Improved Stroke Care in a Primary Stroke Centre Using AI-Decision Support.

Bence Gunda, Ain Neuhaus, Ildikó Sipos, Rita Stang, Péter Pál Böjti, Tímea Takács, Dániel Bereczki, Balázs Kis, István Szikora, George Harston

Open access · goldAbstract read
In one paragraph

Article in Cerebrovascular diseases extra, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 21 citations in OpenAlex.

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  7. A comprehensive guide to digital neurology. An update on current development on digital neurology derived from the Digital Neuro Hub project.Neurological sciences : official journal of the Italian Neurological Society and of the Italian Society of Clinical Neurophysiology · 2025
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  18. Can AI Predict the Need for Surgery in Traumatic Brain Injury?Radiology. Artificial intelligence · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 2 institutions in 2 countries.

Bence GundaDepartment of Neurology, Semmelweis University, Budapest, Hungary.
Ain NeuhausOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Ildikó SiposDepartment of Neurology, Semmelweis University, Budapest, Hungary.
Rita StangDepartment of Neurology, Semmelweis University, Budapest, Hungary.
Péter Pál BöjtiDepartment of Neurology, Semmelweis University, Budapest, Hungary.
Tímea TakácsDepartment of Neurology, Semmelweis University, Budapest, Hungary.
Dániel BereczkiDepartment of Neurology, Semmelweis University, Budapest, Hungary.
Balázs KisNational Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
István SzikoraNational Institute of Mental Health, Neurology and Neurosurgery, Budapest, Hungary.
George HarstonOxford University Hospitals NHS Foundation Trust, Oxford, United Kingdom.
Semmelweis University · HUOxford University Hospitals NHS Trust · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPatient selection for reperfusion therapies requires significant expertise in neuroimaging. Increasingly, machine learning-based analysis is used for faster and standardized patient selection. However, there is little information on how such software influences real-world patient management.

aimsWe evaluated changes in thrombolysis and thrombectomy delivery following implementation of automated analysis at a high volume primary stroke centre.

methodsWe retrospectively collected data on consecutive stroke patients admitted to a large university stroke centre from two identical 7-month periods in 2017 and 2018 between which the e-Stroke Suite (Brainomix, Oxford, UK) was implemented to analyse non-contrast CT and CT angiography results. Delivery of stroke care was otherwise unchanged. Patients were transferred to a hub for thrombectomy. We collected the number of patients receiving intravenous thrombolysis and/or thrombectomy, the time to treatment; and outcome at 90 days for thrombectomy.

results399 patients from 2017 and 398 from 2018 were included in the study. From 2017 to 2018, thrombolysis rates increased from 11.5% to 18.1% with a similar trend for thrombectomy (2.8-4.8%). There was a trend towards shorter door-to-needle times (44-42 min) and CT-to-groin puncture times (174-145 min). There was a non-significant trend towards improved outcomes with thrombectomy. Qualitatively, physician feedback suggested that e-Stroke Suite increased decision-making confidence and improved patient flow.

conclusionsUse of artificial intelligence decision support in a hyperacute stroke pathway facilitates decision-making and can improve rate and time of reperfusion therapies in a hub-and-spoke system of care.

Indexed as

Artificial IntelligenceStrokeComputed Tomography AngiographyHumansRetrospective StudiesThrombectomyTreatment Outcomee-ASPECTSMachine learningStrokeThrombectomyThrombolysis

Identifiers

PMID35134802
PMCPMC9082202
OpenAlexW4210934379

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.