Evidence map›Paper›PMID 35134152›Full record

ArticleClinical infectious diseases : an official publication of the Infectious Diseases Society of America2022

Endocarditis Caused by Nontypeable Streptococcus pneumoniae.

Stefanie S V Henriet, Jeroen D Langereis, Stephanie W Lo, Stephen Bentley, Rob J Mesman, Zina Fejzic, Laura van Niftrik, Nina M van Sorge, Heiman F L Wertheim, Marien I de Jonge and 1 more

Open access · hybridAbstract read
In one paragraph

Article in Clinical infectious diseases : an official publication of the Infectious Diseases Society of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 4 citations in OpenAlex.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Stefanie S V HenrietDepartment of Pediatric Infectious Diseases and Immunology, Amalia Children's Hospital, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Jeroen D LangereisLaboratory of Medical Immunology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Stephanie W LoParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Stephen BentleyParasites and Microbes, Wellcome Sanger Institute, Hinxton, United Kingdom.
Rob J MesmanDepartment of Microbiology, Institute for Water and Wetland Research, Faculty of Science, Radboud University, Nijmegen, The Netherlands.
Zina FejzicDepartment of Pediatric Cardiology, Amalia Children's Hospital, Radboud University Medical Center, Nijmegen, The Netherlands.
Laura van NiftrikDepartment of Microbiology, Institute for Water and Wetland Research, Faculty of Science, Radboud University, Nijmegen, The Netherlands.
Nina M van SorgeDepartment of Medical Microbiology and Infection Prevention and Netherlands Reference Laboratory for Bacterial Meningitis, Amsterdam University Medical Center, University of Amsterdam, Amsterdam, The Netherlands.
Heiman F L WertheimDepartment of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Marien I de JongeLaboratory of Medical Immunology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Amelieke J H CremersDepartment of Medical Microbiology, Radboudumc Center for Infectious Diseases, Radboud University Medical Center, Nijmegen, The Netherlands.
Radboud University Nijmegen · NLRadboud University Medical Center · NLWellcome Sanger Institute · GBAmsterdam University Medical Centers · NL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The Streptococcus pneumoniae capsule is regarded as indispensable in bacteremia. We report an infant with a ventricular septal defect and infective endocarditis caused by nontypeable S. pneumoniae. In-depth investigation confirmed a deficient capsule yet favored pneumococcal fitness for causing infective endocarditis, rather than a host immune disorder, as the cause of infective endocarditis in this case.

Indexed as

EndocarditisEndocarditis, BacterialPneumococcal InfectionsPneumoniaHumansInfantStreptococcus pneumoniaebacterial polysaccharide capsuleinfective endocarditispathogenesisStreptococcus pneumoniae

Identifiers

PMID35134152
PMCPMC9464071
OpenAlexW4210370521

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.