Evidence map›Paper›PMID 35134094›Full record

ArticlePloS one2022

Sex differences in pulmonary function parameters among Indigenous Australians with and without chronic airway disease.

Subash S Heraganahally, Timothy Howarth, Lisa Sorger, Helmi Ben Saad

Erratum issuedAbstract read
In one paragraph

Article in PloS one, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 17 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 1 synthesis or guideline pooled it.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

4 authors.

Subash S HeraganahallyDepartment of Respiratory and Sleep Medicine, Royal Darwin Hospital, Darwin, Northern Territory, Australia.ORCID 0000-0003-0788-7137
Timothy HowarthDarwin Respiratory and Sleep Health, Darwin Private Hospital, Darwin, Northern Territory, Australia.
Lisa SorgerDepartment of Medical Imaging, Royal Darwin Hospital, Darwin, Northern Territory, Australia.ORCID 0000-0001-5470-1118
Helmi Ben SaadFaculty of Medicine of Sousse, Laboratory of Physiology, University of Sousse, Sousse, Tunisia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundStudies assessing normative values and sex differences in pulmonary function test parameters (PFTPs) among Indigenous populations are sparse.

methodsPFTPs were compared between male and female Indigenous Australian adults with and without chest radiologically proven chronic airway diseases (CADs).

results485 adults (56% were female) with no significant difference in age, body mass index or smoking status between sexes were included. Females displayed a higher prevalence of radiology without CADs compared to males (66 vs. 52%, respectively). Among patients without CADs, after adjustment for age, stature and smoking, males displayed significantly higher absolute values of Forced Vital Capacity (FVC) (mean difference, 0.41L (0.21,0.62), p<0.001) and Forced Expiratory Volume in one second (FEV1) (mean difference 0.27L (0.07,0.47), p<0.001), with no significant difference in FEV1/FVC ratio (mean difference -0.02 (-0.06, 0.02), p = 0.174). Male and female patients with radiologically proven CADs demonstrated lower FEV1/FVC values. However, compared to females, males showed significantly greater reductions in pre- [-0.53 (-0.74, -0.32) vs. -0.29 (-0.42, -0.16), p = 0.045] and post- [-0.51 (-0.72, -0.3) vs. -0.27 (-0.39, -0.14), p = 0.049] bronchodilator FEV1.

conclusionsThere are significant sex differences in the PFTPs among Indigenous Australians. Recognising these differences may be of value in the accurate diagnosis, management, monitoring and prognostication of CADs in this population.

Indexed as

Sex FactorsAsthmaAustraliaBronchodilator AgentsFemaleForced Expiratory VolumeHumansIndigenous PeoplesLungMaleMiddle AgedPrevalencePulmonary Disease, Chronic ObstructiveRespirationRespiratory Function TestsRespiratory MechanicsBronchodilator Agents

Identifiers

PMID35134094
PMCPMC8824342

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.