Evidence map›Paper›PMID 35133785›Full record

ArticleACS nano2022

Metallointercalators-DNA Tetrahedron Supramolecular Self-Assemblies with Increased Serum Stability.

M Andrey Joaqui-Joaqui, Zoe Maxwell, Mandapati V Ramakrishnam Raju, Min Jiang, Kriti Srivastava, Fangwei Shao, Edgar A Arriaga, Valérie C Pierre

Open access · greenAbstract read
In one paragraph

Article in ACS nano, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
3.3field-weighted citation impact, top 7% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 41 citations in OpenAlex.

  1. Article
  2. Review
  3. Nano-Bio Interactions between DNA Nanocages and Human Serum Albumin.Journal of chemical theory and computation · 2023
    Article
  4. Review
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 2 countries.

M Andrey Joaqui-JoaquiDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States of America.
Zoe MaxwellDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States of America.
Mandapati V Ramakrishnam RajuDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States of America.
Min JiangZhejiang University-University of Illinois at Urbana-Champaign Institute, Zhejiang University, Haining, 314400, China.
Kriti SrivastavaDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States of America.
Fangwei ShaoZhejiang University-University of Illinois at Urbana-Champaign Institute, Zhejiang University, Haining, 314400, China.
Edgar A ArriagaDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States of America.ORCID 0000-0001-8863-6174
Valérie C PierreDepartment of Chemistry, University of Minnesota, Minneapolis, Minnesota 55455, United States of America.ORCID 0000-0002-0907-8395
University of Minnesota · USUniversity of Illinois Urbana-Champaign · US

Funding

Training Grant: Functional Proteomics of AgingT32AG029796 · NIA · UNIVERSITY OF MINNESOTA · PI EDGAR A ARRIAGA, Douglas G Mashek · 2008 to 2026
$6.6M
Training the Next Generation of Chemical BiologistsT32GM132029 · NIGMS · UNIVERSITY OF MINNESOTA · PI Erin Elizabeth Carlson, William Charles Krause Pomerantz · 2019 to 2026
$2.7M
NIA NIH HHS T32 AG029796NIGMS NIH HHS T32 GM132029
6 · The paper itself

Abstract

Self-assembly of metallointercalators into DNA nanocages is a rapid and facile approach to synthesize discrete bioinorganic host/guest structures with a high load of metal complexes. Turberfield's DNA tetrahedron can accommodate one intercalator for every two base pairs, which corresponds to 48 metallointercalators per DNA tetrahedron. The affinity of the metallointercalator for the DNA tetrahedron is a function of both the structure of the intercalating ligand and the overall charge of the complex, with a trend in affinity [Ru(bpy)

Indexed as

Coordination ComplexesOrganometallic CompoundsRutheniumBase PairingDNAIntercalating AgentsCoordination ComplexesDNAIntercalating AgentsOrganometallic CompoundsRutheniumcell uptakeDNA tetrahedronmetallointercalatorserum stabilitysupramolecular self-assembly

Identifiers

PMID35133785
PMCPMC8926058
OpenAlexW4210927976

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.