Evidence map›Paper›PMID 35133643›Full record

SynthesisEating and weight disorders : EWD2022

Phonological working memory is adversely affected in adults with anorexia nervosa: a systematic literature review.

Amelia D Dahlén, Santino Gaudio, Helgi B Schiöth, Samantha J Brooks

Abstract readSystematic Review
In one paragraph

Synthesis in Eating and weight disorders : EWD, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Neurobiology and Cognition in Girls at High-Risk of Eating Disorders: Exploring Imaging-Derived Trait Markers.European eating disorders review : the journal of the Eating Disorders Association · 2025
    Article
  2. Article
  3. Back to the future: Progressing memory research in eating disorders.The International journal of eating disorders · 2023
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Amelia D DahlénSection of Functional Pharmacology, Department of Neuroscience, Uppsala University, 75124, Uppsala, Sweden. dahlenamelia@gmail.com.ORCID http://orcid.org/0000-0002-5765-1002
Santino GaudioSection of Functional Pharmacology, Department of Neuroscience, Uppsala University, 75124, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-7165-881X
Helgi B SchiöthSection of Functional Pharmacology, Department of Neuroscience, Uppsala University, 75124, Uppsala, Sweden.ORCID http://orcid.org/0000-0001-7112-0921
Samantha J BrooksSection of Functional Pharmacology, Department of Neuroscience, Uppsala University, 75124, Uppsala, Sweden. S.J.Brooks@ljmu.ac.uk.ORCID http://orcid.org/0000-0002-9146-6257

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeCognitive restraint has potentiating and deleterious effects on working memory (WM) in anorexia nervosa (AN). Conflicting evidence may be due to heterogeneity of tasks examining different WM components (e.g., verbal/auditory versus visuospatial), and differences in adolescent versus adult AN. Additionally, differential cognitive profiles of restricting versus binge/purging subtypes, comorbid psychiatric disorders and psychotropic medication use may confound findings.

methodsTo address these conflicts, 25 studies, published between 2016 and 2021, investigating WM in children, adolescents and adults with AN were systematically reviewed using PRISMA guidelines.

resultsIn 71% of WM tasks, no difference in performance between AN patients and age-matched controls was reported, while 29% of WM tasks showed worse performance. Adults with AN displayed deficits in 44% of the verbal/auditory tasks, while performance remained unaffected in 86% of visuospatial tasks.

conclusionExamining age groups and WM subsystems separately revealed novel findings of differentially affected WM components in AN. Comorbidities and psychotropic medications were common among AN participants and should be regarded as critical confounding factors for WM measures. Future studies examining different components of WM, acknowledging these confounding factors, may reveal specific deficits in AN to aid treatment improvement strategies. LEVEL OF EVIDENCE: I, systematic review.

Indexed as

Anorexia NervosaFeeding and Eating DisordersAdolescentAdultChildComorbidityHumansMemory, Short-TermNeuropsychological TestsAnorexic voiceEating disorderPhonological loopVisuospatial sketchpadWorking memory

Identifiers

PMID35133643
PMCPMC9287223

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.