ArticleJournal of community genetics2022
Psychiatric symptoms in a Spanish sample with hereditary cancer risk.
Article in Journal of community genetics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04428710 (Cancer Genetic Counseling and Emotional Response in Spanish Population), which is not on this map. Not yet cited in PubMed.
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Cancer Genetic Counseling and Emotional Response in Spanish Population
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4 authors at 1 institution in 1 country.
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Abstract
objectiveAn integral part of the genetic counselling process is the assessment of psychiatric morbidity. The objectives of this study were first to assess psychometric properties of the General Health Questionnaire (GHQ-28items) in a Spanish sample at increased risk of hereditary cancer, and second evaluated the prevalence of psychiatric morbidity and the contribution of socio-demographic and clinical characteristics to predict distress.
methodsA cross-sectional study was designed with 766 patients. Psychometric analysis with exploratory factor analysis was performed. The influences of socio-demographic characteristics were investigated by multiple linear regression analyses.
resultsFactor analysis supported the four-factor solution of the original GHQ-28; Depression and Social dysfunction scales were more stable than Anxiety and Somatic symptom scales. Psychiatric morbidity was detected in 212 (27.9%) patients. The variables predicting psychiatric morbidity were gender, age, patient affected by cancer, previous psychiatric treatment, and patients with relatives affected by cancer. The higher prevalence of psychiatric symptoms was in the age group from 41 to 59 years (16.73%), women (24.37%), patients affected by cancer (19.89%), patients without previous psychiatric treatment (20.82%), and patients with relatives affected by cancer (21.74%).
conclusionScreening psychological distress should consider socio-demographic and clinical characteristics with reference to improve the quality of care.
trial registrationClinical trials identifier: NCT04428710.
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