Evidence map›Paper›PMID 35132875›Full record

Trial reportJournal of the American Heart Association2022

ABCD-GENE Score and Clinical Outcomes Following Percutaneous Coronary Intervention: Insights from the TAILOR-PCI Trial.

Davide Capodanno, Dominick J Angiolillo, Ryan J Lennon, Shaun G Goodman, Sang-Wook Kim, Fearghas O'Cochlain, Derek Y So, John Sweeney, Charanjit S Rihal, Michael Farkouh and 1 more

Registry-linked trialAbstract readClinical Trial
In one paragraph

Trial report in Journal of the American Heart Association, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06665919 (Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI), which is not on this map. Cited by 18 papers.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06665919 nacompletednot on this mapstarted 2023, after this paper: background citation

Randomized Controlled Trial for Evaluating CYP2C19 Allele Genotype-guided Clopidogrel Treatment Outcomes in Real-world Practice After the ePCI

TypeinterventionalSponsorVistamedi Ltd.Ran2023 to 2025Enrolled283ConditionsCoronary Artery Disease, Clopidogrel Resistance, Coronary Thrombosis, Adverse Cardiac EventsArmsCYP2C19 Genotype-Guided Clopidogrel Treatment, CYP2C19 Genotype Guided Antiplatelet Treatment Alternative to Clopidogrel, The Conventional Clopidogrel Treatment
3 · Its place in the literature

Who cites it

18 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Clopidogrel resistance and its relevance: Current concepts.Journal of family medicine and primary care · 2024
    Review
  6. Article
  7. Effectiveness of Clopidogrel vs Alternative P2YJournal of the American College of Cardiology · 2024
    Article
  8. Article
  9. Review
  10. Review
  11. Article
  12. Pharmacogenetics of P2YPharmacotherapy · 2023
    Review
  13. Pharmacogenetics of Antiplatelet Therapy.Annual review of pharmacology and toxicology · 2023
    Review
  14. Review
  15. Review
  16. Article
  17. Article
  18. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Davide CapodannoDivision of Cardiology Azienda Ospedaliero Universitaria Policlinico "G. Rodolico-San Marco"University of Catania Catania Italy.ORCID 0000-0002-5156-7723
Dominick J AngiolilloDivision of Cardiology University of Florida College of Medicine Jacksonville Florida.ORCID 0000-0001-8451-2131
Ryan J LennonDepartment of Health Sciences Research Mayo Clinic Rochester Minnesota.ORCID 0000-0002-8366-8422
Shaun G GoodmanSt. Michael's HospitalUniversity of Toronto Toronto Ontario Canada.ORCID 0000-0001-8068-2440
Sang-Wook KimChung-Ang University Hospital Seoul Korea.ORCID 0000-0002-7208-8596
Fearghas O'CochlainMayo Clinic Health System - Eau Claire Eau Claire Wisconsin.
Derek Y SoUniversity of Ottawa Heart Institute Ottawa Ontario Canada.ORCID 0000-0002-3909-5698
John SweeneyMayo Clinic Arizona Scottsdale Arizona.
Charanjit S RihalDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota.ORCID 0000-0003-2044-4664
Michael FarkouhSt. Michael's HospitalUniversity of Toronto Toronto Ontario Canada.
Naveen L PereiraDepartment of Cardiovascular Medicine Mayo Clinic Rochester Minnesota.ORCID 0000-0003-3813-3469

Funding

TAILOR PCI: Transitioning a Genotype Based Randomized Clinical Trial to a Registry Using Digital SolutionsU01HL128606 · NHLBI · MAYO CLINIC ROCHESTER · PI FARKOUH, MICHAEL E, PEREIRA, NAVEEN LUKE · 2016 to 2019
$7.0M
Clinical Implementation of Clopidogrel Pharmacogenetics: The TAILOR-PCI Trial - DCCU01HL128626 · NHLBI · MAYO CLINIC ROCHESTER · PI BAILEY, KENT R · 2016 to 2019
$1.9M
NHLBI NIH HHS U01 HL128606NHLBI NIH HHS U01 HL128626
6 · The paper itself

Abstract

Background In TAILOR-PCI, genotype-guided selection of P2Y

Indexed as

Acute Coronary SyndromeMyocardial InfarctionPercutaneous Coronary InterventionStrokeClopidogrelHumansPlatelet Aggregation InhibitorsTreatment OutcomeClopidogrelPlatelet Aggregation Inhibitorsantiplatelet therapygenetic testingischemiapercutaneous coronary intervention

Identifiers

PMID35132875
PMCPMC9245815

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.