Evidence map›Paper›PMID 35132840›Full record

ArticleJournal of Korean medical science2022

Morning Chronotype Decreases the Risk of Chemotherapy-Induced Peripheral Neuropathy in Women With Breast Cancer.

Kyung-Lak Son, Dooyoung Jung, Kwang-Min Lee, Chan-Woo Yeom, Gyu Han Oh, Tae-Yong Kim, Seock-Ah Im, Kyung-Hun Lee, David Spiegel, Bong-Jin Hahm

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT01887925 (The Effects of Per3, Clock Polymorphism on Sleep and Associated Symptoms in Breast Cancer Patients Under Chemotherapy.), which is not on this map. Cited by 2 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01887925 completednot on this map

The Effects of Per3, Clock Polymorphism on Sleep and Associated Symptoms in Breast Cancer Patients Under Chemotherapy.

TypeobservationalSponsorSeoul National University HospitalRan2012 to 2015Enrolled224ConditionsBreast Neoplasms
3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

Kyung-Lak SonDepartment of Neuropsychiatry, Dongguk University Ilsan Hospital, Goyang, Korea.ORCID https://orcid.org/0000-0002-9332-8659
Dooyoung JungDepartment of Biomedical Engineering, Ulsan National Institute of Science and Technology, Ulsan, Korea.ORCID https://orcid.org/0000-0002-5381-4847
Kwang-Min LeeMind Lab Place Psychiatry Clinic, Seoul, Korea.ORCID https://orcid.org/0000-0001-5229-6489
Chan-Woo YeomDepartment of Psychiatry, Uijeongbu Eulji Medical Center, Uijeongbu, Korea.ORCID https://orcid.org/0000-0003-2265-3291
Gyu Han OhPublic Health Medical Service, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-7736-8984
Tae-Yong KimDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-3930-6766
Seock-Ah ImDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-5396-6533
Kyung-Hun LeeDepartment of Internal Medicine, Seoul National University Hospital, Seoul, Korea.ORCID https://orcid.org/0000-0002-2390-3240
David SpiegelDepartment of Psychiatry and Behavioral Sciences, Stanford University, Stanford, CA, USA.ORCID https://orcid.org/0000-0002-9476-9173
Bong-Jin HahmDepartment of Neuropsychiatry, Seoul National University Hospital, Seoul, Korea. hahmbj@gmail.com.ORCID https://orcid.org/0000-0002-2366-3275
Seoul National University · KRSeoul National University Hospital · KRDongguk University Ilsan Hospital · KREulji University · KRStanford University · USUlsan National Institute of Science and Technology · KR

Funding

National Research Foundation of Korea NRF-2013R1A1A2013480
6 · The paper itself

Abstract

backgroundThe purpose of this longitudinal prospective cohort study was to investigate the role of chronotype in the incidence of chemotherapy-induced peripheral neuropathy (CIPN) among women with breast cancer.

methodsWe recruited women with breast cancer awaiting adjuvant chemotherapy, including four cycles of docetaxel. Participants reported peripheral neuropathy symptoms of numbness/tingling at the baseline, and at 4weeks after completion of chemotherapy. Candidate psychiatric factors associated with CIPN were assessed at the baseline, using the Composite Scale of Morningness, the Pittsburgh Sleep Quality Index, and the Hospital Anxiety and Depression Scale. To examine the association between chronotype and CIPN, we built logistic regression models, adjusting for demographic, clinical, and other psychiatric variables.

resultsAmong 48 participants, 29 participants developed CIPN. The morning chronotype was inversely associated with CIPN (odds ratio, 0.06; confidence interval, 0.01-0.74;

conclusionOur results suggest that the morning chronotype is a protective factor against the development of CIPN in patients with breast cancer who were treated with docetaxel.

trial registrationClinicalTrials.gov Identifier: NCT01887925.

Indexed as

AdolescentAdultAgedBreast NeoplasmsChemotherapy, AdjuvantFemaleHumansLongitudinal StudiesMiddle AgedPeripheral Nervous System DiseasesProspective StudiesRepublic of KoreaYoung AdultAdjuvant ChemotherapyBreast CancerChemotherapy-Induced Peripheral NeuropathyChronotype

Identifiers

PMID35132840
PMCPMC8822114
OpenAlexW4220824351

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.