Evidence map›Paper›PMID 35132839›Full record

ArticleJournal of Korean medical science2022

Flat Pattern Peaks of Tacrolimus Absorption and Associated Pharmacogenomic Variants in Kidney Transplantation Recipients.

Suh Min Kim, Younggyun Lim, Sangil Min, Byung-Joo Min, Myung-Eui Seo, Kye Hwa Lee, Ju Han Kim, Jongwon Ha

Open access · goldAbstract read
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
1.0field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 7 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Suh Min Kim *Department of Surgery, Chung-Ang University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-3221-2190
Younggyun Lim *Seoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-4548-4662
Sangil MinDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-0688-0278
Byung-Joo MinSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0001-9097-8114
Myung-Eui SeoSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-6978-4961
Kye Hwa LeeDepartment of Information Medicine, Asan Medical Center, University of Ulsan College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0002-7593-7020
Ju Han KimSeoul National University Biomedical Informatics (SNUBI), Division of Biomedical Informatics, Seoul National University College of Medicine, Seoul, Korea. juhan@snu.ac.kr.ORCID https://orcid.org/0000-0003-1522-9038
Jongwon HaDepartment of Surgery, Seoul National University College of Medicine, Seoul, Korea.ORCID https://orcid.org/0000-0003-2285-3517
Seoul National University · KRChung-Ang University · KRUlsan College · KR

Funding

Chung-Ang UniversitySeoul National University Hospital 3020160260
6 · The paper itself

Abstract

backgroundTacrolimus is the most commonly used immunosuppressive drug in solid organ transplantation. After administering a conventional twice-daily dose of tacrolimus, peak levels were achieved within the first 1.5 to 2 hours. A group of patients showed different early absorption phase of tacrolimus after kidney transplantation.

methodsTrough(C

resultsTwenty-eight patients showed flat pattern peaks. The mean C

conclusionBoth of C

Indexed as

Kidney TransplantationPharmacogenomic VariantsFemaleHumansMaleMiddle AgedTacrolimusTacrolimusKidney TransplantationPharmacogenomicsTacrolimus

Identifiers

PMID35132839
PMCPMC8822115
OpenAlexW4206453443

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.