Evidence map›Paper›PMID 35132838›Full record

ArticleJournal of Korean medical science2022

Dermatomyositis Following BNT162b2 mRNA COVID-19 Vaccination.

Wesam Gouda, Anwar Albasri, Faisal Alsaqabi, Humoud Y Al Sabah, Marwan Alkandari, Hassan Abdelnaby

Open access · goldAbstract readCase Reports
In one paragraph

Article in Journal of Korean medical science, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed, 2 pooled it
6.2field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed, 2 syntheses or guidelines pooled it, 41 citations in OpenAlex.

  1. Pooled it
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  11. A case of Anti-MDA5-Positive dermatomyositis after inactivated COVID-19 vaccine.Journal of the European Academy of Dermatology and Venereology : JEADV · 2023
    Article
  12. Article
  13. Review
  14. Onset of amyopathic dermatomyositis following mRNA-based SARS-CoV-2 vaccination.Journal of the European Academy of Dermatology and Venereology : JEADV · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 5 institutions in 2 countries.

Wesam GoudaDepartment of Rheumatology, Faculty of Medicine, Al Azhar University, Assiut, Egypt.ORCID https://orcid.org/0000-0001-6753-3811
Anwar AlbasriDepartment of Rheumatology, Al-Sabah Hospital, Kuwait, Kuwait.ORCID https://orcid.org/0000-0003-2367-6727
Faisal AlsaqabiDepartment of Rheumatology, Al-Sabah Hospital, Kuwait, Kuwait.ORCID https://orcid.org/0000-0001-5308-0284
Humoud Y Al SabahAsad Al Hamad Dermatology Center, Kuwait, Kuwait.ORCID https://orcid.org/0000-0001-9638-6283
Marwan AlkandariDepartment of Radiodiagnosis, Al-Sabah Hospital, Kuwait, Kuwait.ORCID https://orcid.org/0000-0002-6761-0079
Hassan AbdelnabyDepartment of Endemic and Infectious Diseases, Faculty of Medicine, Suez Canal University, Ismailia, Egypt.ORCID https://orcid.org/0000-0002-5393-1912
Al-Sabah Hospital · KWAdan Hospital · KWAl-Azhar University · EGKuwait Institute for Medical Specialization · KWSuez Canal University · EG

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dermatomyositis (DM) is one of the uncommon multi-organ idiopathic inflammatory myopathies that has been reported following the hepatitis B, Influenza, tetanus toxoid, H1N1, and BCG vaccines. However, an association with the coronavirus disease 2019 (COVID-19) vaccine is yet to be reported. In this case, we present the case of a 43-year-old Asian Indian female who was diagnosed with DM 10 days after receiving the second dosage of BNT162b2 mRNA COVID-19 vaccination, in the absence of any additional triggering factors. The diagnosis was established based on physical examination, serological antibodies, magnetic resonance imaging of the muscles, skin biopsy, and electromyography. She received standard treatment for DM, including oral high doses of prednisolone, hydroxychloroquine, mycophenolate, and physiotherapy. The treatment successfully reversed skin changes and muscle weakness. This is the first reported case of classic DM complicated by interstitial lung disease following COVID-19 vaccination. More clinical and functional studies are needed to elucidate this association. Clinicians should be aware of this unexpected adverse event following COVID-19 vaccination and arrange for appropriate management.

Indexed as

AdultBNT162 VaccineCOVID-19DermatomyositisElectromyographyFemaleHumansLung Diseases, InterstitialMagnetic Resonance ImagingMuscle, SkeletalSARS-CoV-2SkinVaccinationBNT162 VaccineAdverse Event Following ImmunizationCOVID-19Creatinine PhosphokinaseDermatomyositismRNA VaccinesMyopathyMyositisVaccination

Identifiers

PMID35132838
PMCPMC8822116
OpenAlexW4210889468

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.