Evidence map›Paper›PMID 35132348›Full record

ArticleOxidative medicine and cellular longevity2022

Sodium Butyrate Ameliorates Oxidative Stress-Induced Intestinal Epithelium Barrier Injury and Mitochondrial Damage through AMPK-Mitophagy Pathway.

Xin Li, Chunchun Wang, Jiang Zhu, Qian Lin, Minjie Yu, Jiashu Wen, Jie Feng, Caihong Hu

Open access · hybridAbstract read
In one paragraph

Article in Oxidative medicine and cellular longevity, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
95citing papers in PubMed, 2 pooled it
21.0field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

95 citing papers in PubMed, 2 syntheses or guidelines pooled it, 144 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Trial
  4. Nutrients · 2026
    Article
  5. Article
  6. Sodium Butyrate MitigatesVeterinary sciences · 2026
    Article
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35 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Xin LiCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.ORCID https://orcid.org/0000-0002-7624-0882
Chunchun WangCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.
Jiang ZhuCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.
Qian LinCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.
Minjie YuCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.
Jiashu WenCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.
Jie FengCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.
Caihong HuCollege of Animal Science, Zhejiang University, Hangzhou 310058, China.ORCID https://orcid.org/0000-0001-5445-4532
Ministry of Education of the People's Republic of China · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sodium butyrate has gained increasing attention for its vast beneficial effects. However, whether sodium butyrate could alleviate oxidative stress-induced intestinal dysfunction and mitochondrial damage of piglets and its underlying mechanism remains unclear. The present study used a hydrogen peroxide- (H

Indexed as

AMP-Activated Protein KinasesAnimalsAntioxidantsBeclin-1Butyric AcidCell LineDNA, MitochondrialEpithelial CellsGene ExpressionHydrogen PeroxideIntestinal MucosaMAP Kinase Signaling SystemMembrane Potential, MitochondrialMitochondriaMitophagyOxidative StressAMP-Activated Protein KinasesAntioxidantsBeclin-1Butyric AcidDNA, MitochondrialHydrogen PeroxideReactive Oxygen SpeciesRNA, Messenger

Identifiers

PMID35132348
PMCPMC8817854
OpenAlexW4213176698

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.