Evidence map›Paper›PMID 35132237›Full record

ReviewBritish journal of cancer2022

Incidence trends for twelve cancers in younger adults-a rapid review.

Erica di Martino, Lesley Smith, Stephen H Bradley, Scott Hemphill, Judy Wright, Cristina Renzi, Rebecca Bergin, Jon Emery, Richard D Neal

Open access · hybridAbstract readReview
In one paragraph

Review in British journal of cancer, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 46 papers.

0numbers the graph read from it
0cells of the map it votes in
46citing papers in PubMed
16.8field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

46 citing papers in PubMed, 83 citations in OpenAlex.

  1. Trial
  2. Review
  3. Article
  4. Trends in Female Breast Cancer Incidence among Japanese, Korean, and US Populations: An Age-Period-Cohort Analysis.Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology · 2026
    Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Observational
  10. Review
  11. Incidence trends of colorectal cancer in young adults in Spain.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2026
    Review
  12. Article
  13. Article
  14. Article
  15. Gender differences between dyadic coping and emotional distress in young and middle-aged cancer patients and spouses.Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer · 2025
    Article
  16. Review
  17. Article
  18. Review
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 2 countries.

Erica di MartinoDivision of Primary Care, Public Health & Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Worsley Building, Clarendon Way, Leeds, LS2 9NL, UK. e.dimartino@leeds.ac.uk.ORCID http://orcid.org/0000-0001-6703-1707
Lesley SmithDivision of Primary Care, Public Health & Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Worsley Building, Clarendon Way, Leeds, LS2 9NL, UK.
Stephen H BradleyDivision of Primary Care, Public Health & Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Worsley Building, Clarendon Way, Leeds, LS2 9NL, UK.
Scott HemphillDivision of Primary Care, Public Health & Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Worsley Building, Clarendon Way, Leeds, LS2 9NL, UK.
Judy WrightAcademic Unit of Health Economics, Leeds Institute of Health Sciences, University of Leeds, Worsley Building, Clarendon Way, Leeds, LS2 9NL, UK.
Cristina RenziEpidemiology of Cancer Healthcare and Outcomes Research Group, Department of Behavioural Science and Health, Institute of Epidemiology & Health Care, University College London, London, UK.ORCID http://orcid.org/0000-0003-3845-9493
Rebecca BerginCentre for Cancer Research, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria Comprehensive Cancer Centre, 305 Grattan Street, Melbourne, VIC, 3000, Australia.
Jon EmeryCentre for Cancer Research, Faculty of Medicine, Dentistry and Health Sciences, University of Melbourne, Victoria Comprehensive Cancer Centre, 305 Grattan Street, Melbourne, VIC, 3000, Australia.ORCID http://orcid.org/0000-0002-5274-6336
Richard D NealDivision of Primary Care, Public Health & Palliative Care, Leeds Institute of Health Sciences, University of Leeds, Worsley Building, Clarendon Way, Leeds, LS2 9NL, UK.
University of Leeds · GBThe University of Melbourne · AUUniversity College London · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Many cancer referral guidelines use patient's age as a key criterium to decide who should be referred urgently. A recent rise in the incidence of colorectal cancer in younger adults has been described in high-income countries worldwide. Information on other cancers is more limited. The aim of this rapid review was to determine whether other cancers are also increasing in younger age groups, as this may have important implications for prioritising patients for investigation and referral. We searched MEDLINE, Embase and Web of Science for studies describing age-related incidence trends for colorectal, bladder, lung, oesophagus, pancreas, stomach, breast, ovarian, uterine, kidney and laryngeal cancer and myeloma. 'Younger' patients were defined based on NICE guidelines for cancer referral. Ninety-eight studies met the inclusion criteria. Findings show that the incidence of colorectal, breast, kidney, pancreas, uterine cancer is increasing in younger age groups, whilst the incidence of lung, laryngeal and bladder cancer is decreasing. Data for oesophageal, stomach, ovarian cancer and myeloma were inconclusive. Overall, this review provides evidence that some cancers are increasingly being diagnosed in younger age groups, although the mechanisms remain unclear. Cancer investigation and referral guidelines may need updating in light of these trends.

Indexed as

Colorectal NeoplasmsMultiple MyelomaNeoplasmsUterine NeoplasmsAdultFemaleHumansIncidenceReferral and Consultation

Identifiers

PMID35132237
PMCPMC9090760
OpenAlexW4213345984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.