ArticleNature biomedical engineering2022
Rapid and ultrasensitive electromechanical detection of ions, biomolecules and SARS-CoV-2 RNA in unamplified samples.
Article in Nature biomedical engineering, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 95 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
95 citing papers in PubMed, 316 citations in OpenAlex.
- Rapid-Forming Conductive Antifouling Hydrogel Coating Enables Magnetically Guided Electrochemical POCT for Direct at‑Home Blood Testing.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026Article
- Rigid tetrahedral DNA nanostructures on graphene-assisted plasmonic sensor for highly sensitive infrared fingerprinting.Analytical and bioanalytical chemistry · 2026Article
- Intimate Interaction Between Nucleic Acid and Conjugated Polymers in Organic Electrochemical Transistors Enables Ultrasensitive Biomarker Detection.Advanced materials (Deerfield Beach, Fla.) · 2026Article
- A transistor-based point-of-care assay with lipid-capped sensory interface for clinical profiling of cardiovascular diseases.National science review · 2026Article
- Spherical Nucleic Acid Stabilized Cage Type Three-Dimensional Electrochemiluminescence Probe for Sensitive and Amplification-Free Diagnosis of Infectious Diseases.Exploration (Beijing, China) · 2026Article
- Nucleic Acid-Based Field-Effect Transistor Biosensors.Biosensors · 2026Review
- Ultrasensitive and long-lasting bioluminescence immunoassay for point-of-care viral antigen detection.Nature biomedical engineering · 2025Article
- Soft bioelectronics embedded with self-confined tetrahedral DNA circuit for high-fidelity chronic wound monitoring.Nature communications · 2025Article
- Designing the Future of Biosensing: Advances in Aptamer Discovery, Computational Modeling, and Diagnostic Applications.Biosensors · 2025Review
- A biochemical sensor with continuous extended stability in vivo.Nature biomedical engineering · 2025Article
- Electro-switchable addressing system for achieving repetitive random data access.Nucleic acids research · 2025Article
- Future perspectives of GMO detection in agriculture: strategies for electrochemical nucleic acid detection.Mikrochimica acta · 2025Review
- Advances in 2D materials for wearable biomonitoring.Materials science & engineering. R, Reports : a review journal · 2025Article
- Rigid DNA Frameworks Anchored Transistor Enabled Ultrasensitive Detection of Aβ-42 in Serum.Sensors (Basel, Switzerland) · 2025Article
- Self-Assembly of Nanogold Triplets on Trimeric Viral Proteins for Infectious Disease Diagnosis.ACS nano · 2025Article
- Biosensors based on organic transistors for intraoral biomarker detection.Mikrochimica acta · 2025Review
- Integration Strategies and Formats in Field-Effect Transistor Chemo- and Biosensors: A Critical Review.ACS sensors · 2025Review
- Porous GNPs assisted LAMP-CRISPR/Cas12a amperometric biosensor as a potential point of care testing system for SARS-CoV-2.Mikrochimica acta · 2025Article
- High Strength, Strain, and Resilience of Gold Nanoparticle Reinforced Eutectogels for Multifunctional Sensors.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Article
- A Brief Review of Aptamer-Based Biosensors in Recent Years.Biosensors · 2025Review
35 more citing papers are in PubMed but not listed here.
Corrections and comments
- Commented on by
Authors and funding
15 authors at 5 institutions in 1 country.
Funding
Abstract
The detection of samples at ultralow concentrations (one to ten copies in 100 μl) in biofluids is hampered by the orders-of-magnitude higher amounts of 'background' biomolecules. Here we report a molecular system, immobilized on a liquid-gated graphene field-effect transistor and consisting of an aptamer probe bound to a flexible single-stranded DNA cantilever linked to a self-assembled stiff tetrahedral double-stranded DNA structure, for the rapid and ultrasensitive electromechanical detection (down to one to two copies in 100 μl) of unamplified nucleic acids in biofluids, and also of ions, small molecules and proteins, as we show for Hg
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.