Evidence map›Paper›PMID 35131940›Full record

ArticleProceedings of the National Academy of Sciences of the United States of America2022

A peptide toxin in ant venom mimics vertebrate EGF-like hormones to cause long-lasting hypersensitivity in mammals.

David A Eagles, Natalie J Saez, Bankala Krishnarjuna, Julia J Bradford, Yanni K-Y Chin, Hana Starobova, Alexander Mueller, Melissa E Reichelt, Eivind A B Undheim, Raymond S Norton and 4 more

Open access · greenAbstract read
In one paragraph

Article in Proceedings of the National Academy of Sciences of the United States of America, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.5field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Article
  2. Toxins in disguise: Neuropeptide mimicry across animal venoms.General and comparative endocrinology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

David A EaglesInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-1646-3566
Natalie J SaezInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.
Bankala KrishnarjunaMonash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.ORCID 0000-0002-4575-0011
Julia J BradfordSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-7184-9309
Yanni K-Y ChinInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-3367-6897
Hana StarobovaInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0001-9401-1744
Alexander MuellerInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-7447-1310
Melissa E ReicheltSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Eivind A B UndheimCentre for Biodiversity Dynamics, Department of Biology, Norwegian University of Science and Technology, 7491 Trondheim, Norway.
Raymond S NortonMonash Institute of Pharmaceutical Sciences, Monash University, Melbourne, VIC 3052, Australia.ORCID 0000-0001-8893-0584
Walter G ThomasSchool of Biomedical Sciences, The University of Queensland, Brisbane, QLD 4072, Australia.
Irina VetterInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-3594-9588
Glenn F KingInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia.ORCID 0000-0002-2308-2200
Samuel D RobinsonInstitute for Molecular Bioscience, The University of Queensland, Brisbane, QLD 4072, Australia; sam.robinson@uq.edu.au.ORCID 0000-0002-3518-0377
The University of Queensland · AUAustralian Research Council · AUMonash University · AUUniversity of Oslo · NO

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Venoms are excellent model systems for studying evolutionary processes associated with predator-prey interactions. Here, we present the discovery of a peptide toxin, MIITX

Indexed as

Drug HypersensitivityAmino Acid SequenceAnimalsAntsAnt VenomsEpidermal Growth FactorInsect Bites and StingsMiceMolecular MimicryToxins, BiologicalAnt VenomsEpidermal Growth FactorToxins, Biologicalconvergent evolutionEGFRErbBGilbertian mimicrymimicry

Identifiers

PMID35131940
PMCPMC8851504
OpenAlexW4210829144

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.