Evidence map›Paper›PMID 35131815›Full record

ArticleBMJ open2022

Development of chronic kidney disease influenced by serum urate and body mass index based on young-to-middle-aged Japanese men: a propensity score-matched cohort study.

Akihiro Kuma, Kosuke Mafune, Bungo Uchino, Yoko Ochiai, Kazuhiko Enta, Akihiko Kato

Open access · goldAbstract read
In one paragraph

Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
0.7field-weighted citation impact, top 33% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 6 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Article
  4. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 4 institutions in 4 countries.

Akihiro KumaKidney Centre, Hospital of the University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan kuma-aki@med.uoeh-u.ac.jp.ORCID 0000-0002-4242-7921
Kosuke MafuneDepartment of Mental Health, Institution of Industrial Ecological Sciences, University of Occupational and Environmental Health, Kitakyushu, Fukuoka, Japan.ORCID 0000-0001-7762-4143
Bungo UchinoHealth Promotion Centre, Yamaha Motor Co Ltd, Iwata, Shizuoka, Japan.
Yoko OchiaiHealth Promotion Centre, Yamaha Motor Co Ltd, Iwata, Shizuoka, Japan.
Kazuhiko EntaHealth Care Centre, Central Japan Railway Company, Nagoya, Aichi, Japan.
Akihiko KatoBlood Purification Unit, Hamamatsu University Hospital, Hamamatsu, Shizuoka, Japan.
University of Occupational and Environmental Health Japan · JPYamaha (Japan) · JPHamamatsu University Hospital · JPHealth Care Foundation · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo investigate the association between serum uric acid (SUA) level and body mass index (BMI) on the development of chronic kidney disease (CKD) in working men aged 20-60 years.

designRetrospective cohort study.

settingData from employees' annual health check-ups were collected from two companies in 2009 and 2014.

participantsA total of 16 708 working men were recruited. We excluded participants with missing essential data (N=7801), who had basal estimated glomerular filtration rate (eGFR) <60.0 mL/min/1.73 m PRIMARY OUTCOME: eGFR <60 mL/min/1.73 m

resultsThe cut-off values of SUA for incident CKD were 6.6 mg/dL in both young (20-39 years old) and middle-aged (40-60 years old) men analysed by receiver operator characteristics. ORs for incident CKD were assessed on propensity score-matched (1:1) cohorts. In young participants (N=1938), after propensity score matching, a coexistence of high-level SUA (≥6.6 mg/dL) and overweight (BMI ≥25 kg/m

conclusionThese findings suggest that high-level SUA is strongly associated with incident CKD in overweight young adult men.

Indexed as

Renal Insufficiency, ChronicUric AcidAdultBody Mass IndexCohort StudiesGlomerular Filtration RateHumansJapanMaleMiddle AgedPropensity ScoreRetrospective StudiesRisk FactorsYoung AdultUric Acidchronic renal failureironother metabolicporphyriaquality in health care

Identifiers

PMID35131815
PMCPMC8823083
OpenAlexW4210830091

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.