ArticleBMJ open2022
Determinants of HIV infection among children born from mothers on prevention of mother to child transmission programme of HIV in southern Ethiopia: a case-control study.
Article in BMJ open, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 26 citations in OpenAlex.
- Magnitude and risk factors of mother-to-child transmission of HIV among HIV-exposed infants after Option B+ implementation in Ethiopia: a systematic review and meta-analysis.AIDS research and therapy · 2024Pooled it
- HIV Status and Its Associated Factors of Children Born to HIV-Positive Mothers on ART at Gambella Public Hospitals, South West Ethiopia, 2024.AIDS and behavior · 2026Article
- HIV positivity rate, mother-to-child transmission and associated factors among HIV exposed infants in Western Ethiopia: a cross-sectional study.BMC pediatrics · 2026Article
- Predictors of HIV Vertical Transmission in Exposed Infants in Northwest, Ethiopia: A Retrospective Cohort Study.Health science reports · 2026Article
- Contributory factors to partial implementation of prevention of mother to child transmission policy in South Africa.BMC pregnancy and childbirth · 2025Article
- HIV-1 Drug Resistance in Children and Implications for Pediatric Treatment Strategies: A Systematic Review and Meta-analysis.Open forum infectious diseases · 2025Review
- Mother-to-Child Transmission of Human Immunodeficiency Virus and Its Determinants: Lessons Learnt from the Test and Treat Strategy at a Regional Hospital in Cameroon.Turkish archives of pediatrics · 2025Article
- Adherence, perceptions and knowledge of an HIV PMTCT programme: A mother-baby pair study.Southern African journal of HIV medicine · 2025Article
- Prevalence and Predictors of Mother-to-Child Transmission of Human Immunodeficiency Virus (HIV) among HIV-exposed Infants.International journal of MCH and AIDS · 2025Article
- Machine learning prediction of adolescent HIV testing services in Ethiopia.Frontiers in public health · 2024Article
- Effect of Dolutegravir-Based First-Line Antiretroviral Therapy on Mother-to-Child Transmission of HIV Among HIV-Exposed Infants in Ethiopia: a Before-and-After Study.HIV/AIDS (Auckland, N.Z.) · 2024Article
- Incidence of HIV Infection among HIV-Exposed Iinfants at Gondar University Hospital from 2019-2021: A Prospective Cohort Study.Ethiopian journal of health sciences · 2023Article
- Article
- Predictors of Retention Among HIV Exposed Infants in the Early Infant Diagnosis Program in Lilongwe Rural, Malawi.Sage open pediatricsArticle
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Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveThis study was aimed to identify determinants of HIV infection among children born from mothers on the prevention of mother to child transmission (PMTCT) programme in Southern Ethiopia. It was designed to explore the main contributors to the considerable transmission rate of HIV from mother to child. SETTING AND
designA multicentre facility-based unmatched case-control study was conducted using 27 health facilities providing PMTCT service in Southern Ethiopia.
participantsOut of 307 (62 cases and 245 controls) expected to participate in this study, a total of 290 mother-child pairs of 58 cases and 232 controls have completed the interview. Cases were children born to mothers on PMTCT programme and with DNA PCR or antibody HIV positive test result at ≤24 months of age. Controls were children born to mothers on PMTCT programme and with DNA PCR or antibody HIV negative test result at ≤24 months of age.
resultData were collected from the mother and record and analysed using SPSS V.20. Logistic regression analysis was done for statistical association and the significance of association was declared at a p value of <0.05. Rural residence (adjusted OR (AOR): 4.15, 95% CI: (1.57 to 10.97)), knowing serostatus during current pregnancy (AOR: 5.11, 95% CI: (1.33 to 19.69)), home delivery (AOR: 6.00, 95% CI: (2.310 to 15.593)), poor partner involvement (AOR: 5.95, 95% CI: 1.91 to 18.53)), poor adherence, late enrolment of the child for ARV prophylaxis (AOR: 4.89, 95% CI: 1.34 to 17.88)), mixed breastfeeding practice (AOR: 10.36, 95% CI: (3.10 to 34.60)) and failure to be on cotrimoxazole therapy (AOR: 7.56, 95% CI: 2.07 to 27.61)) were factors significantly associated with MTCT.
conclusionThe finding implies that more needs to be done on rural residents, strengthening screening for HIV before pregnancy, encouraging male involvement, early enrolment of child for ARV prophylaxis, avoiding mixed breast feeding and putting newborn on cotrimoxazole therapy.
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