Evidence map›Paper›PMID 35131658›Full record

ReviewBiomedicine & pharmacotherapy = Biomedecine & pharmacotherapie2022

Antiviral effects of azithromycin: A narrative review.

Saeed Khoshnood, Maryam Shirani, Amine Dalir, Melika Moradi, Mohammad Hossein Haddadi, Nourkhoda Sadeghifard, Faezeh Sabet Birjandi, Ilya Yashmi, Mohsen Heidary

Open access · goldAbstract readReview
In one paragraph

Review in Biomedicine & pharmacotherapy = Biomedecine & pharmacotherapie, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 1 synthesis or guideline pooled it, 28 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

Saeed KhoshnoodClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Maryam ShiraniToxicology Research Center, Medical Basic Sciences Research Institute, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Amine DalirDepartment of Microbiology, Faculty of Medicine, Iran University of Medical Sciences, Tehran, Iran; Medical Complex Clinical Research Development Center (RCRDC), Iran University of Medical Sciences, Tehran, Iran.
Melika MoradiDepartment of Microbiology, School of Medicine, Ahvaz Jundishapur University of Medical Sciences, Ahvaz, Iran.
Mohammad Hossein HaddadiClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Nourkhoda SadeghifardClinical Microbiology Research Center, Ilam University of Medical Sciences, Ilam, Iran.
Faezeh Sabet BirjandiDepartment of Microbiology and Virology, School of Medicine, Mashhad University of Medical Sciences, Mashhad, Iran.
Ilya YashmiCellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran.
Mohsen HeidaryCellular and Molecular Research Center, Sabzevar University of Medical Sciences, Sabzevar, Iran; Department of Laboratory Sciences, School of Paramedical Sciences, Sabzevar University of Medical Sciences, Sabzevar, Iran. Electronic address: mohsenheidary40@gmail.com.
Medical University of Ilam · IRAhvaz Jundishapur University of Medical Sciences · IRSabzevar University of Medical Sciences · IRIran University of Medical Sciences · IRMashhad University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Viral infections have a great impact on human health. The urgent need to find a cure against different viruses led us to investigations in a vast range of drugs. Azithromycin (AZT), classified as a macrolide, showed various effects on different known viruses such as severe acute respiratory syndrome coronavirus (SARS-CoV), Zika, Ebola, Enterovirus (EVs) and Rhinoviruses (RVs), and Influenza A previously; namely, these viruses, which caused global concerns, are considered as targets for AZT different actions. Due to AZT background in the treatment of known viral infections mentioned above (which is described in this study), in the early stages of COVID-19 (a new zoonotic disease caused by a novel coronavirus called severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2)) development, AZT drew attention to itself due to its antiviral and immunomodulatory effects as a valuable candidate for COVID-19 treatment. AZT usage instructions for treating different viral infections have always been under observation, and COVID-19 is no exception. There are still debates about the use of AZT in COVID-19 treatment. However, eventually, novel researches convinced WHO to announce the discontinuation of AZT use (alone or in combination with hydroxychloroquine) in treating SARS-CoV-2 infection. This research aims to study the structure of all of the viruses mentioned above and the molecular and clinical effects of AZT against the virus.

Indexed as

COVID-19 Drug TreatmentAnti-Bacterial AgentsAntiviral AgentsAzithromycinEbolavirusHumansInfluenza A virusSARS-CoV-2Severe acute respiratory syndrome-related coronavirusZika VirusAnti-Bacterial AgentsAntiviral AgentsAzithromycinAzithromycinCOVID-19EbolaEnterovirus and RhinovirusesInfluenza ASARS-CoVSARS-CoV-2Viral infectionsZika

Identifiers

PMID35131658
PMCPMC8813546
OpenAlexW4210562796

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.