Evidence map›Paper›PMID 35131286›Full record

ArticleBrain research2022

Regulation of dark period sleep by the Amygdala: A microinjection and optogenetics study.

Laurie L Wellman, Gyorgy Lonart, Austin M Adkins, Larry D Sanford

Open access · greenAbstract read
In one paragraph

Article in Brain research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.1field-weighted citation impact, top 27% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Laurie L WellmanSleep Research Laboratory, Center for Integrative Neuroscience and Inflammatory Diseases, Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA 23507, USA. Electronic address: wellmall@evms.edu.
Gyorgy LonartSleep Research Laboratory, Center for Integrative Neuroscience and Inflammatory Diseases, Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA 23507, USA. Electronic address: lonartg@evms.edu.
Austin M AdkinsSleep Research Laboratory, Center for Integrative Neuroscience and Inflammatory Diseases, Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA 23507, USA. Electronic address: adkinsam@evms.edu.
Larry D SanfordSleep Research Laboratory, Center for Integrative Neuroscience and Inflammatory Diseases, Pathology and Anatomy, Eastern Virginia Medical School, Norfolk, VA 23507, USA. Electronic address: sanforld@evms.edu.
Eastern Virginia Medical School · US

Funding

Role of amygdalar inputs to locus coeruleus in sleep regulationR21MH105770 · NIMH · EASTERN VIRGINIA MEDICAL SCHOOL · PI LONART, GYORGY, SANFORD, LARRY D · 2014 to 2015
$403k
NIMH NIH HHS R21 MH105770
6 · The paper itself

Abstract

The central nucleus of the amygdala (CNA) projects to brainstem regions that generate and regulate rapid eye movement sleep (REM). We used optogenetics to assess the influence of CNA inputs into reticularis pontis oralis (RPO), pedunculopontine tegmentum (PPT) and nucleus subcoeruleus (SubC) on dark period sleep. We compared these results to effects of microinjections into CNA of the GABA

Indexed as

Central Amygdaloid NucleusOptogeneticsAnimalsElectroencephalographyMaleMicroinjectionsMuscimolRatsRats, WistarSleepTetrodotoxinWakefulnessMuscimolTetrodotoxinAmygdalaCentral nucleusOptogeneticsRapid eye movement sleepReticularis pontis oralisTetrodotoxin

Identifiers

PMID35131286
PMCPMC8901558
OpenAlexW4210488917

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.