Evidence map›Paper›PMID 35131255›Full record

ArticleThe Journal of investigative dermatology2022

Incorporating Patient-Reported Outcomes as a Vital Sign for Dermatologic Clinical Care and Clinical Investigations.

Aaron M Secrest, Mary-Margaret Chren

Abstract read
In one paragraph

Article in The Journal of investigative dermatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed.

  1. Trial
  2. Article
  3. Article
  4. Qualitative study of patient-reported outcome data collection among clinicians in dermatology at a single academic center.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
    Article
  5. Article
  6. Severity strata and minimally important differences of CompAQ and Skindex-16 for patients with acne.Journal of the European Academy of Dermatology and Venereology : JEADV · 2026
    Article
  7. Article
  8. Article
  9. Article
  10. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Aaron M SecrestDepartment of Dermatology, University of Utah School of Medicine, Salt Lake City, Utah, USA; Department of Population Health Sciences, University of Utah School of Medicine, Salt Lake City, Utah, USA.
Mary-Margaret ChrenDepartment of Dermatology, Vanderbilt University Medical Center, Nashville, Tennessee, USA. Electronic address: mary-margaret.chren@vumc.org.

Funding

The e-Itch Vital Signs: development of a new mobile outcomes measure for clinical trials in patients with chronic itchR01AR073001 · NIAMS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI CHREN, MARY-MARGARET · 2018 to 2020
$640k
NIAMS NIH HHS R01 AR073001
6 · The paper itself

Abstract

Patient-reported outcomes (PROs) provide quantitative assessments of patients' experiences with their skin diseases. PROs are usually much more comprehensive than what can be gleaned from a brief clinical history and more informative than what dermatologists can gather on clinical examination. Correlations between PROs and clinician assessments (e.g., investigator global assessment, PASI) are poor to moderate at best, and therefore data from each source are not redundant and can complement one another. PROs should serve as skin vital signs in dermatology. PROs can offer snapshots of the intensity of a symptom as well as the effects of symptoms, emotions, and functioning on a patient's skin-related QOL. Just as clinicians obtain a baseline blood pressure before starting antihypertensives, dermatology-specific PROs serve as a baseline from which clinicians can monitor (even remotely) for improvement or side effects with treatment and for flares. Both PROs and conventional vital signs are usually normal. It is when they are abnormal or different than expected that they become informative. We conclude by offering a roadmap for investigators to conduct the next steps in PRO research necessary to establish guidelines for transitioning PROs from clinical research and trials to routine clinical use.

Indexed as

Drug-Related Side Effects and Adverse ReactionsSkin DiseasesHumansPatient Reported Outcome MeasuresQuality of LifeVital Signs

Identifiers

PMID35131255
PMCPMC9133171

What OpenQuestion holds

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LicenceTDM
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.