Evidence map›Paper›PMID 35131216›Full record

ArticleJournal of medical imaging and radiation sciences2022

Intensity of hypermetabolic axillary lymph nodes in oncologic patients in relation to timeline following COVID-19 vaccination.

Ning Su, Christiane Wiefels, Ran Klein, Wanzhen Zeng, Farzad Abbaspour

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Article in Journal of medical imaging and radiation sciences, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. Observational
  5. Article
  6. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Ning SuDivision of Nuclear Medicine, Department of Medicine, The Ottawa Hospital and University of Ottawa, 1053 Carling Ave, Ottawa, ON, K1Y 4E9, Canada.
Christiane WiefelsDivision of Nuclear Medicine, Department of Medicine, The Ottawa Hospital and University of Ottawa, 1053 Carling Ave, Ottawa, ON, K1Y 4E9, Canada; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada.; Federal Fluminense University, Niteroi, Rio de Janeiro, Brazil.
Ran KleinDivision of Nuclear Medicine, Department of Medicine, The Ottawa Hospital and University of Ottawa, 1053 Carling Ave, Ottawa, ON, K1Y 4E9, Canada; Division of Cardiology, Department of Medicine, University of Ottawa Heart Institute, Ottawa, Canada.; Department of Systems and Computer Engineering, Carleton University, Ottawa, Canada.
Wanzhen ZengDivision of Nuclear Medicine, Department of Medicine, The Ottawa Hospital and University of Ottawa, 1053 Carling Ave, Ottawa, ON, K1Y 4E9, Canada.
Farzad AbbaspourDivision of Nuclear Medicine, Department of Medicine, The Ottawa Hospital and University of Ottawa, 1053 Carling Ave, Ottawa, ON, K1Y 4E9, Canada. Electronic address: fabbaspour@toh.ca.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeFirst discovered in Wuhan, China in December 2019, severe acute respiratory syndrome coronavirus 2 (SARS-COV-2) is a highly contagious and deadly novel virus that quickly wreaked havoc throughout the world. As mass vaccination are now underway worldwide, clinicians have started to encounter a new clinical entity, COVID-19 vaccine-associated axillary lymphadenopathy. This presents a unique challenge to medical imagers, particularly in oncologic patients.

methodsIn this retrospective study, we assessed metabolic activity, size, and timeline of COVID-19 vaccine-associated axillary hypermetabolic lymph nodes in 202 oncologic patients post vaccination with 18-fluorodeoxyglucose positron emission tomography (18-FDG PET).

resultsWhen present, COVID-19 vaccine-associated hypermetabolic lymph nodes demonstrate a mean maximum standard uptake value (SUV

conclusionBased on our preliminary results, we would recommend correlation with a history and time of vaccination and routine use of a pre-study patient questionnaire to guide interpretation to prevent over-diagnosis of axillary nodal metastases and/or unnecessary work-up in oncologic patients.

Indexed as

COVID-19COVID-19 VaccinesHumansLymph NodesPositron Emission Tomography Computed TomographyRetrospective StudiesSARS-CoV-2VaccinationCOVID-19 VaccinescoronavirusCOVID-19FDG PET/CTlymphadenopathy

Identifiers

PMID35131216
PMCPMC8769936

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.