Evidence map›Paper›PMID 35130367›Full record

ArticleJournal of medical virology2022

Association of atrial fibrillation with infectivity and severe complications of COVID-19: A nationwide cohort study.

Jin Park, Jae Il Shin, Dong-Hyeok Kim, Junbeom Park, Jimin Jeon, Jinkwon Kim, Tae-Jin Song

Open access · bronzeAbstract read
In one paragraph

Article in Journal of medical virology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
2.0field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Jin ParkDepartment of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Jae Il ShinDepartment of Pediatrics, Yonsei University College of Medicine, Seoul, Korea.ORCID 0000-0003-2326-1820
Dong-Hyeok KimDepartment of Cardiology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.ORCID 0000-0002-6339-8496
Junbeom ParkDepartment of Cardiology, Mokdong Hospital, Ewha Womans University College of Medicine, Seoul, Korea.
Jimin JeonDepartment of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin-si, Korea.ORCID 0000-0003-1497-3914
Jinkwon KimDepartment of Neurology, Yongin Severance Hospital, Yonsei University College of Medicine, Yongin-si, Korea.ORCID 0000-0003-0156-9736
Tae-Jin SongDepartment of Neurology, Seoul Hospital, Ewha Womans University College of Medicine, Seoul, Korea.ORCID 0000-0002-9937-762X
Ewha Womans University · KRYonsei University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Infection is associated with the occurrence, recurrence, and progression of atrial fibrillation (AF), and is also closely related to poor prognosis. However, studies of the relationship between infectivity and severe complications of coronavirus infectious disease-19  (COVID-19) with a history of AF are limited. To estimate infectivity and severity of complications in COVID-19 patients with a history of AF, this study was done. From the Korean nationwide COVID-19 dataset, 212 678 participants with at least one severe acute respiratory syndrome coronavirus 2 (COVID-19) test were included between January 1 and June 4, 2020. AF was defined according to at least two outpatient hospital visits or one admission with an ICD-10 code of "I48" before the COVID-19 test. To investigate the association of AF with infectivity and severe complications of COVID-19, 1:4 ratio propensity score matching (PSM) was performed. Severe complications of COVID-19 were defined as a composite outcome of mechanical ventilation, intensive care unit admission, and death within 2 months after COVID-19 diagnosis. Among 212 678 participants who underwent the COVID-19 test, there were 7713 COVID-19 positive patients. After PSM, COVID-19 PCR positivity did not show a significant difference according to the presence of AF (odds ratio [OR]: 0.79, 95% confidence interval [CI]: [0.60-1.04]). Of 7713 COVID-19 patients, 62 (0.8%) had a history of AF and severe complications occurred in 444 (5.7%) patients. After PSM, AF was associated with the development of severe complications (OR: 2.04, 95% CI: [1.10-3.79]) and mortality (OR: 2.09, 95% CI: [1.01-4.31]) of COVID-19. We found that AF was associated with an increased risk of severe complications in COVID-19 infected patients.

Indexed as

Atrial FibrillationCOVID-19Cohort StudiesCOVID-19 TestingHumansRisk FactorsSARS-CoV-2atrial fibrillationCOVID-19infectivityintensive care unitmechanical ventilationmortalityprognosis

Identifiers

PMID35130367
PMCPMC9088370
OpenAlexW4210253606

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.