Evidence map›Paper›PMID 35130121›Full record

ReviewPrion2022

Creutzfeldt-Jakob disease associated with a T188K homozygous mutation in the prion protein gene: a case report and review of the literature.

Yuheng Shan, Jiatang Zhang, Yuying Cen, Xiaojiao Xu, Ruishu Tan, Jiahua Zhao, Shengyuan Yu

Abstract readCase ReportsReview
In one paragraph

Review in Prion, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Sporadic Creutzfeldt-jakob disease: a case report.Journal of medical case reports · 2026
    Article
  2. Prion Mutations in Republic of Republic of Korea, China, and Japan.International journal of molecular sciences · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Yuheng ShanMedical School of Chinese PLA, Beijing, P.R. China.
Jiatang ZhangDepartment of Neurology, The First Medical Centre, Chinese PLA General Hospital, Beijing, P.R. China.ORCID 0000-0002-9714-0944
Yuying CenMedical School of Chinese PLA, Beijing, P.R. China.
Xiaojiao XuMedical School of Chinese PLA, Beijing, P.R. China.
Ruishu TanMedical School of Chinese PLA, Beijing, P.R. China.
Jiahua ZhaoMedical School of Chinese PLA, Beijing, P.R. China.
Shengyuan YuDepartment of Neurology, The First Medical Centre, Chinese PLA General Hospital, Beijing, P.R. China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic Creutzfeldt-Jakob disease (gCJD) is a prion disease caused by mutations in the prion protein gene (

Indexed as

Creutzfeldt-Jakob SyndromePrionsFemaleHomozygoteHumansMutationPrion ProteinsPrion ProteinsPrionsCreutzfeldt–Jakob diseasehomozygoteprion protein geneT188K

Identifiers

PMID35130121
PMCPMC8824217

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.