Evidence map›Paper›PMID 35130109›Full record

Trial reportGut microbes

Lucas Wauters, Luka Van Oudenhove, Alison Accarie, Karlien Geboers, Hannelore Geysen, Joran Toth, Anja Luypaerts, Kristin Verbeke, Tamara Smokvina, Jeroen Raes and 2 more

Open access · goldAbstract readRandomized Controlled Trial
In one paragraph

Trial report in Gut microbes. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 1 pooled it
2.7field-weighted citation impact, top 9% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Trial
  4. Nutrients · 2023
    Trial
  5. Trial
  6. Review
  7. Review
  8. Review
  9. Review
  10. Review
  11. The therapeutic effects ofGut microbiome (Cambridge, England) · 2025
    Review
  12. Review
  13. Review
  14. Effects of aNutrients · 2023
    Article
  15. Article
  16. Article
  17. Article
  18. Review
  19. Preclinical Safety Assessment ofMicroorganisms · 2022
    Article
  20. Gut microbes
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 3 institutions in 3 countries.

Lucas WautersDepartment of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-3195-4996
Luka Van OudenhoveTranslational Research in Gastrointestinal Disorders Ku Leuven, Leuven, Belgium.
Alison AccarieTranslational Research in Gastrointestinal Disorders Ku Leuven, Leuven, Belgium.
Karlien GeboersDepartment of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.
Hannelore GeysenTranslational Research in Gastrointestinal Disorders Ku Leuven, Leuven, Belgium.
Joran TothTranslational Research in Gastrointestinal Disorders Ku Leuven, Leuven, Belgium.
Anja LuypaertsDepartment of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.
Kristin VerbekeTranslational Research in Gastrointestinal Disorders Ku Leuven, Leuven, Belgium.ORCID 0000-0002-5352-7565
Tamara SmokvinaDanone Nutricia Research, Palaiseau, France.
Jeroen RaesVib Center for Microbiology, Leuven, Belgium.
Jan TackDepartment of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0002-3206-6704
Tim VanuytselDepartment of Gastroenterology and Hepatology, University Hospitals Leuven, Leuven, Belgium.ORCID 0000-0001-8728-0903
KU Leuven · BEDanone (France) · FRRega Institute for Medical Research · BE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Psychological stress negatively affects the intestinal barrier function in animals and humans. We aimed to study the effect of

Indexed as

Academic PerformanceAdultHealthy VolunteersHumansHydrocortisoneLacticaseibacillus rhamnosusMaleProbioticsStress, PsychologicalStudentsYoung AdultHydrocortisonegut-brain interactionLactobacillus rhamnosuspermeabilityprobioticstress

Identifiers

PMID35130109
PMCPMC8824214
OpenAlexW4210747958

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.