Evidence map›Paper›PMID 35130095›Full record

ArticleThe international journal of lower extremity wounds2022

Cutaneous Small-vessel Vasculitis after ChAdOx1 COVID-19 Vaccination: A Report of Five Cases.

Ji An Uh, Soo Kyung Lee, Joong Ho Kim, Jae Ho Lee, Myoung Shin Kim, Un Ha Lee

Abstract readCase Reports
In one paragraph

Article in The international journal of lower extremity wounds, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ji An Uh65509Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.ORCID https://orcid.org/0000-0002-4202-9843
Soo Kyung Lee65509Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
Joong Ho Kim65509Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
Jae Ho Lee65509Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
Myoung Shin Kim65509Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.
Un Ha Lee65509Inje University Sanggye Paik Hospital, Seoul, Republic of Korea.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amidst the Coronavirus Disease 2019 (COVID-19) pandemic, vaccination against severe acute respiratory syndrome 2 (SARS-CoV-2) is recommended for everyone over 18 years in South Korea, with the exception of pregnant women. Unexpected adverse cutaneous reactions after the COVID-19 vaccination have been recently reported. Cutaneous small-vessel vasculitis (CSVV) predominantly affects small blood vessels, defined as small intraparenchymal arteries, arterioles, capillaries, and venules, without any detectable involvement of non-cutaneous organs. We report five cases of CSVV after the ChAdOx1 COVID-19 vaccination in 44- to 68-year-old women. The symptoms commonly appeared within 2 days after vaccination. The lesion was localized to the lower limbs in four patients and spread to the upper limbs in one patient. All patients demonstrated a favorable response to oral methylprednisolone, antihistamines, and topical steroids. Considering the importance of the COVID-19 vaccination, clinicians should be aware of CSVV as a potential adverse event. Further studies are required to elucidate the causative link and pathogenesis.

Indexed as

COVID-19VasculitisAdultAgedCOVID-19 VaccinesFemaleHumansMiddle AgedPregnancySARS-CoV-2VaccinationCOVID-19 VaccinesautoimmunityChAdOx1 COVID-19 vaccineCOVID-19vasculitis

Identifiers

PMID35130095
PMCPMC8832129

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.