Evidence map›Paper›PMID 35129879›Full record

ArticleJournal of veterinary emergency and critical care (San Antonio, Tex. : 2001)2022

Acute kidney injury manifesting as renal tubular acidosis with proximal and distal renal tubular dysfunction in a dog with acute pancreatitis.

James C Barton, Peter-John Mäntylä Noble, Erin M O'Connell

Open access · hybridAbstract readCase Reports
In one paragraph

Article in Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 6 citations in OpenAlex.

  1. Article
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  5. Retrospective Evaluation of the Prognosis and Prevalence of Hyperchloremia in Dogs and Cats.Journal of veterinary emergency and critical care (San Antonio, Tex. : 2001)
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

James C BartonDepartment of Small Animal Clinical Sciences, Institute of Veterinary Science, University of Liverpool, Neston, UK.ORCID https://orcid.org/0000-0002-6636-2085
Peter-John Mäntylä NobleDepartment of Small Animal Clinical Sciences, Institute of Veterinary Science, University of Liverpool, Neston, UK.
Erin M O'ConnellDepartment of Small Animal Clinical Sciences, Institute of Veterinary Science, University of Liverpool, Neston, UK.
University of Liverpool · GB

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo describe the clinical presentation and management of a critically ill dog with profound renal tubular acidosis (RTA) with proximal and distal renal tubular dysfunction. CASE SUMMARY: A 3-year-old neutered female Border Terrier was presented with frequent regurgitation resulting from acute pancreatitis with severe ileus. Venous acid-base analysis and complete urinalysis confirmed the presence of normal anion gap metabolic acidosis with inappropriately alkaline urine (pH 8), consistent with distal RTA. Urinalysis, urine amino acids, and urinary fractional excretion of electrolytes revealed glycosuria (with normoglycemia), aminoaciduria, and increased fractional excretion of sodium, calcium, and phosphate consistent with generalized proximal renal tubulopathy or Fanconi syndrome. The dog responded well to supportive care and alkaline therapy and made a complete recovery. NEW OR UNIQUE INFORMATION PROVIDED: To the authors' knowledge, this is the first description of RTA with proximal and distal renal tubular dysfunction in the veterinary literature. Furthermore, the authors hypothesize that the transient RTA was a manifestation of acute kidney injury secondary to acute pancreatitis, the first report of this in the literature.

Indexed as

AcidosisAcidosis, Renal TubularAcute Kidney InjuryDog DiseasesPancreatitisAcute DiseaseAnimalsDogsFemalecanineglomerular filtration ratekidney injurymetabolic acidosistubulopathy

Identifiers

PMID35129879
PMCPMC9545851
OpenAlexW4210911868

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.