Evidence map›Paper›PMID 35129646›Full record

ArticleEuropean journal of nutrition2022

Dietary B group vitamin intake and the bladder cancer risk: a pooled analysis of prospective cohort studies.

Iris W A Boot, Anke Wesselius, Evan Y W Yu, Maree Brinkman, Piet van den Brandt, Eric J Grant, Emily White, Elisabete Weiderpass, Pietro Ferrari, Matthias B Schulze and 4 more

Open access · hybridAbstract read
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Article in European journal of nutrition, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 10 institutions in 9 countries.

Iris W A BootDepartment of Complex Genetics and Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40 (Room C5.570), 6229 ER, Maastricht, The Netherlands.
Anke WesseliusDepartment of Complex Genetics and Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40 (Room C5.570), 6229 ER, Maastricht, The Netherlands. anke.wesselius@maastrichtuniversity.nl.ORCID http://orcid.org/0000-0003-4474-9665
Evan Y W YuDepartment of Complex Genetics and Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40 (Room C5.570), 6229 ER, Maastricht, The Netherlands.
Maree BrinkmanDepartment of Complex Genetics and Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40 (Room C5.570), 6229 ER, Maastricht, The Netherlands.
Piet van den BrandtDepartment of Epidemiology, Schools for Oncology and Developmental Biology and Public Health and Primary Care, Maastricht University Medical Centre, Maastricht, The Netherlands.
Eric J GrantDepartment of Epidemiology Radiation Effects Research Foundation, Hiroshima, Japan.
Emily WhiteFred Hutchinson Cancer Research Center, Seattle, WA, USA.
Elisabete WeiderpassInternational Agency for Research on Cancer World Health Organization, Lyon, France.
Pietro FerrariInternational Agency for Research on Cancer World Health Organization, Lyon, France.
Matthias B SchulzeDepartment of Molecular Epidemiology, German Institute of Human Nutrition Potsdam-Rehbruecke, Nuthetal, Germany.
Bas Bueno-de-MesquitaDepartment for Determinants of Chronic Diseases, National Institute for Public Health and the Environment, Bilthoven, The Netherlands.
Maria Jose-SanchezEscuela Andaluza de Salud Publia, Granada, Spain.
Bjorn GyllingDepartment of Medical Biosciences, Pathology, Umeå University, Umeå, Sweden.
Maurice P ZeegersDepartment of Complex Genetics and Epidemiology, School of Nutrition and Translational Research in Metabolism, Maastricht University, Universiteitssingel 40 (Room C5.570), 6229 ER, Maastricht, The Netherlands.
Maastricht University · NLCentre international de recherche sur le cancer · FRCancer Council Victoria · AUFred Hutch Cancer Center · USMaastricht University Medical Centre · NLNational Institute for Public Health and the Environment · NLRadiation Effects Research Foundation · JPUmeå University · SEUniversidad de Granada · ESUniversity of Potsdam · DE

Funding

COHORT STUDY OF DIETARY SUPPLEMENTS AND CANCER RISKR01CA074846 · NCI · FRED HUTCHINSON CANCER RESEARCH CENTER · PI WHITE, EMILY · 1999 to 2005
$6.8M
NCI NIH HHS R01 CA074846NCI NIH HHS (R01CA74846)World Health Organization 001
6 · The paper itself

Abstract

purposeDiet may play an essential role in the aetiology of bladder cancer (BC). The B group complex vitamins involve diverse biological functions that could be influential in cancer prevention. The aim of the present study was to investigate the association between various components of the B group vitamin complex and BC risk.

methodsDietary data were pooled from four cohort studies. Food item intake was converted to daily intakes of B group vitamins and pooled multivariate hazard ratios (HRs), with corresponding 95% confidence intervals (CIs), were obtained using Cox-regression models. Dose-response relationships were examined using a nonparametric test for trend.

resultsIn total, 2915 BC cases and 530,012 non-cases were included in the analyses. The present study showed an increased BC risk for moderate intake of vitamin B1 (HR

conclusionOur findings highlight the importance of future research on the food sources of B group vitamins in the context of the overall and sex-stratified diet.

Indexed as

Urinary Bladder NeoplasmsVitamin B ComplexCohort StudiesDietFemaleHumansMaleProspective StudiesRisk FactorsThiamineVitamin AVitamin B 12ThiamineVitamin AVitamin B 12Vitamin B ComplexB group vitaminsBladder cancerNutritional oncologyPooled cohort analysis

Identifiers

PMID35129646
PMCPMC9279207
OpenAlexW4210847003

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.