Evidence map›Paper›PMID 35129631›Full record

ArticleEuropean archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery2022

The association between laryngopharyngeal reflux and insomnia.

Jeong Wook Kang, Jung Min Park, Young Chan Lee, Young-Gyu Eun

Abstract read
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In one paragraph

Article in European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.2field-weighted citation impact, top 24% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 7 citations in OpenAlex.

  1. European clinical practice guideline: managing and treating laryngopharyngeal reflux disease.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2026
    Guideline
  2. Review
  3. Article
  4. Laryngopharyngeal reflux and insomnia.European archives of oto-rhino-laryngology : official journal of the European Federation of Oto-Rhino-Laryngological Societies (EUFOS) : affiliated with the German Society for Oto-Rhino-Laryngology - Head and Neck Surgery · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Jeong Wook KangDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, #23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea.
Jung Min ParkDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, #23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea.
Young Chan LeeDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, #23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea.
Young-Gyu EunDepartment of Otolaryngology-Head and Neck Surgery, School of Medicine, Kyung Hee University, #23 Kyungheedae-ro, Dongdaemun-gu, Seoul, 02447, Korea. ygeun@hanmail.net.ORCID http://orcid.org/0000-0003-4081-5207
Kyung Hee University · KR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the prevalence of insomnia in patients with laryngopharyngeal reflux (LPR) and to analyze the relationship between the severity of insomnia and LPR-related symptoms.

methodsWe analyzed 69 patients with LPR and 61 healthy controls. The LPR was confirmed via the 24-h hypopharyngeal-esophageal multichannel intraluminal impedance pH monitoring. Reflux symptoms and sleep disturbances were assessed using the Reflux Symptom Index and Insomnia Severity Index. We compared the prevalence of insomnia between the two groups. We analyzed the relationship between reflux symptoms and severity of insomnia.

resultsThe prevalence of insomnia was significantly higher in patients with LPR than in healthy controls (46.3% vs. 29.5%; p = 0.049). The severity of reflux-related symptoms was correlated with insomnia severity (rho = 0.44; p < 0.001). Patients with LPR with nighttime reflux were more likely to have sleep disturbances than patients with LPR without nighttime reflux.

conclusionPatients with LPR are more likely to experience insomnia than healthy controls, and the severity of reflux symptoms was related to the severity of insomnia.

Indexed as

Esophagitis, PepticLaryngopharyngeal RefluxSleep Initiation and Maintenance DisordersElectric ImpedanceEsophageal pH MonitoringHumansHypopharynxImpedance monitoringInsomniaLaryngopharyngeal refluxPharyngeal refluxpH monitoring

Identifiers

PMID35129631
OpenAlexW4210888761

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.