Evidence map›Paper›PMID 35129418›Full record

ArticleGlobal spine journal2023

Risk Factors for Postoperative Ileus in Patients Undergoing Spine Surgery.

Nathan R Hendrickson, Yue Zhang, Linda Amoafo, Zane Randell, Michaela Rasmussen, Michelle Zeidan, Pete Shorten, Darrel S Brodke, Nicholas Spina, Brandon D Lawrence and 1 more

Open access · goldAbstract read
In one paragraph

Article in Global spine journal, 2023. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 10 citations in OpenAlex.

  1. Trial
  2. Early postoperative hypophosphatemia is an independent predictor of ileus after transforaminal lumbar interbody fusion: a multicenter retrospective cohort study.European spine journal : official publication of the European Spine Society, the European Spinal Deformity Society, and the European Section of the Cervical Spine Research Society · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Nathan R HendricksonDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.
Yue ZhangDivision of Epidemiology, University of Utah, Salt Lake City, UT, USA.
Linda AmoafoPopulation Health Sciences, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0002-3306-8445
Zane RandellDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.
Michaela RasmussenDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.
Michelle ZeidanDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.
Pete ShortenDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.
Darrel S BrodkeDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-8749-3765
Nicholas SpinaDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0002-3264-9774
Brandon D LawrenceDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0001-7530-7451
W Ryan SpikerDepartment of Orthopaedic Surgery, University of Utah, Salt Lake City, UT, USA.ORCID 0000-0003-1758-5335
University of Utah · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

STUDY

designRetrospective Cohort Study.

objectivesPostoperative ileus (POI) is a common complication following elective spinal surgeries. The aim of this study was to determine the incidence of POI and identify demographic and surgical risk factors for developing POI after elective instrumented fusion of the thoracolumbar spine.

methodsThe University of Utah Institutional Review Board (IRB) approved this retrospective study. The study does not require informed consent given the data reviewed was deidentified and collected in accordance with the institution's standard of care. A designated IRB committee determined that study is exempt under exemption category 7. IRB approval number 00069703. Patients undergoing instrumented thoracolumbar fusion for one or more levels were retrospectively identified from an internal spine surgery database. Cases performed for trauma, infection, or tumors were excluded. Demographics, medical comorbidities, surgical variables, and opioid medication administration (morphine milligram equivalents, MME) were abstracted from the electronic medical record. Univariate analysis was used to identify variables associated with POI. These variables were then tested for independent association with POI using multivariate logistic regression.

results418 patients were included in the current study. The incidence of POI was 9.3% in this cohort. There was no significant relationship between development of POI and patient age, gender, BMI, diabetes mellitus, thyroid dysfunction, lung disease, CKD, GERD, smoking status, alcohol abuse, anemia, or prior abdominal surgery. Univariate analysis demonstrated significant association between POI and fusion ≥7 levels compared to fusions of fewer levels (

conclusionsThis retrospective cohort study demonstrates that greater postoperative MME is an independent risk factor for POI after thoracolumbar spine fusion when accounting for demographic, medical, and surgical variables with multiple logistic regression. Prospective studies are warranted to evaluate clinical measures to decrease the risk of POI among patients undergoing instrumented thoracolumbar spinal fusions.

Indexed as

complicationsileusopioidspine surgery

Identifiers

PMID35129418
PMCPMC10538340
OpenAlexW4210883258

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.