Evidence map›Paper›PMID 35129332›Full record

ArticleJournal of chemical information and modeling2022

BINANA 2: Characterizing Receptor/Ligand Interactions in Python and JavaScript.

Jade Young, Neerja Garikipati, Jacob D Durrant

Abstract read
In one paragraph

Article in Journal of chemical information and modeling, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.

0numbers the graph read from it
0cells of the map it votes in
21citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

21 citing papers in PubMed.

  1. Article
  2. Article
  3. Impact of C-Terminal AmideMolecules (Basel, Switzerland) · 2026
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. MAGPIE: An interactive tool for visualizing and analyzing protein-ligand interactions.Protein science : a publication of the Protein Society · 2024
    Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
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  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Jade YoungDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
Neerja GarikipatiDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.
Jacob D DurrantDepartment of Biological Sciences, University of Pittsburgh, Pittsburgh, Pennsylvania 15260, United States.ORCID 0000-0002-5808-4097

Funding

Advancing drug-lead and chemical-probe discovery using weighted-ensemble simulations and biophysical validationR01GM132353 · NIGMS · UNIVERSITY OF PITTSBURGH AT PITTSBURGH · PI DURRANT, JACOB D · 2019 to 2023
$1.7M
NIGMS NIH HHS R01 GM132353
6 · The paper itself

Abstract

BINding ANAlyzer (BINANA) is an algorithm for identifying and characterizing receptor/ligand interactions and other factors that contribute to binding. We recently updated BINANA to make the algorithm more accessible to a broader audience. We have also ported the Python3 codebase to JavaScript, thus enabling BINANA analysis in the web browser. As proof of principle, we created a web-browser application so students and chemical-biology researchers can quickly visualize receptor/ligand complexes and their unique binding interactions.

Indexed as

AlgorithmsSoftwareHumansInternetLigandsWeb BrowserLigands

Identifiers

PMID35129332
PMCPMC8889568

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.