ArticleKorean circulation journal2022
Prognostic Impact of Left Atrial Strain After Mitral Valve Repair Surgery in Patients With Severe Mitral Regurgitation.
Article in Korean circulation journal, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.
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Who cites it
10 citing papers in PubMed, 1 synthesis or guideline pooled it, 16 citations in OpenAlex.
- Pooled it
- Changes in echocardiographic parameters and strain and outcomes following mitral valve repair: insight from new mitral regurgitation classifications.Frontiers in cardiovascular medicine · 2025Article
- Impact of left atrial strain on clinical outcomes in patients with permanent pacemaker implantation.ESC heart failure · 2024Article
- 2023 Korean Society of Echocardiography position paper for the diagnosis and management of valvular heart disease, part II: mitral and tricuspid valve disease.Journal of cardiovascular imaging · 2024Review
- Mitral Annular Velocity in Primary MR: Unveiling the Prognostic Potential of an Oldie But Goodie.Korean circulation journal · 2024Article
- Cardiac Structural and Functional Remodeling After Transcatheter Mitral Valve in Valve Implantation: Early Changes and Prognostic Significance.Structural heart : the journal of the Heart Team · 2024Article
- The Role of the Left Atrium: From Multimodality Imaging to Clinical Practice: A Review.Life (Basel, Switzerland) · 2022Review
- Current Unmet Needs and Clues to the Solution in the Management of Tricuspid Regurgitation.Korean circulation journal · 2022Review
- Expanding Role of Left Atrial Strain in Valvular Heart Disease.Korean circulation journal · 2022Article
- Potential Diagnostic and Prognostic Values of Left Atrial Strain in Valvular Heart Disease.Journal of cardiovascular echographyReview
Corrections and comments
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Authors and funding
10 authors at 3 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
BACKGROUND AND
objectivesThe prognostic value of left atrial (LA) function in terms of long-term clinical outcomes after mitral regurgitation (MR) surgery remains unclear. Therefore, we investigated the impact of preoperative LA global longitudinal strain (LAGLS) on the long-term postoperative clinical outcomes in chronic severe MR patients who underwent mitral valve (MV) repair surgery.
methodsFrom January 2012 to December 2017, we analyzed 338 patients (mean age, 51.9±12.5 years; 218 males [64.5%]) treated with MV repair surgery for severe MR. The primary outcome was cardiovascular events, defined as the composite of all-cause death, newly developed atrial fibrillation (AF), and re-hospitalization for cardiovascular causes.
resultsDuring a median follow-up of 45 months (interquartile range, 26-65), 30 (8.9%) cardiovascular events, 5 (1.5%) all-cause death, 8 (2.4%) newly developed AF, and 26 (7.7%) re-hospitalizations occurred. On multivariable analysis, baseline LAGLS was an independent predictor of cardiovascular events (adjusted hazard ratio [HR], 0.91; 95% confidential interval [CI], 0.85-0.97; p=0.004) and re-hospitalization (adjusted HR, 0.93; 95% CI, 0.86-1.00; p=0.037). According to the optimal cutoff value of LAGLS, patients with low LAGLS (<23.6%) had a significantly higher risk of cardiovascular events (adjusted HR, 2.70; 95% CI, 1.04-7.00; p=0.041) than those with high LAGLS (≥23.6%). In a subgroup analysis, patients with high LAGLS had better clinical outcomes regardless of whether the patient had a LA volume index <60 mL/m².
conclusionsIn patients with chronic severe MR who received successful MV repair surgery, preoperative LAGLS is an independent predictor of long-term postoperative outcomes.
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