Evidence map›Paper›PMID 35129244›Full record

ArticleJournal of applied microbiology2022

Analysis of hypervirulent Klebsiella pneumoniae and classic Klebsiella pneumoniae infections in a Chinese hospital.

Dongjie Chen, Yingrui Zhang, Jiafang Wu, Jun Li, Han Chen, Xiaoguang Zhang, Xinlan Hu, Falin Chen, Rongguo Yu

Open access · hybridAbstract read
In one paragraph

Article in Journal of applied microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed, 1 pooled it
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Connections betweenInfection and immunity · 2026
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  4. Prevalence, Risk Factors, and Clinical Outcomes of HypervirulentIndian journal of critical care medicine : peer-reviewed, official publication of Indian Society of Critical Care Medicine · 2025
    Article
  5. Article
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  7. Article
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  9. Article
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  11. Clinical Spectrum and Outcomes of CryptogenicPathogens (Basel, Switzerland) · 2023
    Article
  12. Article
  13. Article
  14. Epidemiological Features ofInfection and drug resistance · 2022
    Article
  15. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Dongjie ChenShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Yingrui ZhangShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Jiafang WuShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Jun LiShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Han ChenShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Xiaoguang ZhangShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Xinlan HuShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Falin ChenShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.
Rongguo YuShengli Clinical Medical, College of Fujian Medical University, Fuzhou, China.ORCID https://orcid.org/0000-0002-9519-050X
Fujian Medical University · CN

Funding

Fujian Natural Science Foundation 2020J05258Fujian Provincial Hospital (2017)510#Fujian Provincial Hospital 2020HSJJ09Health Science and Technology Program of Fujian Province 2020GGA006
6 · The paper itself

Abstract

aimsTo evaluate the clinical and genetic virulence characteristics of critically ill patients with hypervirulent Klebsiella pneumoniae (hvKP) and classic KP (cKP) infection. METHODS AND

resultsThe patients included in this retrospective study (n = 225) were grouped according to their hvKP (n = 114) or cKP (n = 111) status, and their clinical characteristics were analysed and compared. Cox multivariate analysis was conducted to determine the risk factors for hvKP infection. Length of hospital stay, length of intensive care unit stay, duration of mechanical ventilation and 28-day survival rate were similar between the groups. However, the incidence of septic shock was higher in the hvKP group (16.7%) than in the cKP group (8.1%).

conclusionsThere was a high rate of hvKP infection in this population. Compared to patients with cKP infection, those with hvKP infection showed a higher probability of having septic shock; nevertheless, survival and length of hospital stay were similar between the groups. Risk factors for hvKP infection included hospital-acquired infection and renal insufficiency. SIGNIFICANCE AND IMPACT OF THE STUDY: This study presents relevant information on the characteristics of hvKP infection in a Chinese population, and this promotes early diagnosis and supports the view that the prevalence of hvKP is high in China.

Indexed as

Klebsiella InfectionsShock, SepticChinaHospitalsHumansKlebsiella pneumoniaeRetrospective Studiesclassic Klebsiella pneumoniaehypervirulent Klebsiella pneumoniaeinfectionrisk factorsseptic shock

Identifiers

PMID35129244
PMCPMC9305427
OpenAlexW4210623305

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.