Evidence map›Paper›PMID 35129232›Full record

ArticleAddiction (Abingdon, England)2022

Relationship between high-risk alcohol consumption and severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroconversion: a prospective sero-epidemiological cohort study among American college students.

Sina Kianersi, Christina Ludema, Jonathan T Macy, Chen Chen, Molly Rosenberg

Open access · greenAbstract read
In one paragraph

Article in Addiction (Abingdon, England), 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.

0numbers the graph read from it
0cells of the map it votes in
15citing papers in PubMed
2.6field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

15 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. [Development and Validation of a Risk Prediction Model for Secondary Pulmonary Infarction in Elderly Patients With Acute Pulmonary Embolism].Sichuan da xue xue bao. Yi xue ban = Journal of Sichuan University. Medical science edition · 2026
    Article
  3. Review
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  6. Changes in alcohol consumption among medical students during the COVID-19 pandemic - results from POLLEK study.International journal of occupational medicine and environmental health · 2023
    Article
  7. Substances of abuse and their effect on SAR-CoV-2 pathogenesis.NeuroImmune pharmacology and therapeutics · 2023
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Sina KianersiDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.ORCID 0000-0003-0950-2675
Christina LudemaDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.ORCID 0000-0003-0779-810X
Jonathan T MacyDepartment of Applied Health Science, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.ORCID 0000-0003-2925-8585
Chen ChenDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.
Molly RosenbergDepartment of Epidemiology and Biostatistics, Indiana University School of Public Health-Bloomington, Bloomington, IN, USA.ORCID 0000-0001-6679-6791
Indiana University Bloomington · US

Funding

Minding A Mid-America Gap: NIDA/NIAAA Epidemiology Research Training for Clinical Researchers and Clinicians in Currently Under-Served AreasR25DA051249 · NIDA · MICHIGAN STATE UNIVERSITY · PI BARONDESS, DAVID · 2020 to 2021
$606k
NIDA NIH HHS R25 DA051249
6 · The paper itself

Abstract

aimsTo estimate the associations between high-risk alcohol consumption and (1) severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) seroconversion, (2) self-reported new SARS-CoV-2 infection and (3) symptomatic COVID-19.

designProspective cohort study.

settingIndiana University Bloomington (IUB), IN, USA.

participantsA total of 1027 IUB undergraduate students (64% female), aged 18 years or older, residing in Monroe County, Indiana, seronegative for SARS-CoV-2 at study baseline. MEASUREMENTS: Primary exposure was high-risk alcohol consumption measured with an Alcohol Use Disorders Identification Test (AUDIT) questionnaire score of 8 or more. Primary outcome was SARS-CoV-2 seroconversion since baseline, assessed with two SARS-CoV-2 antibody tests, at baseline (September 2020) and end-line (November 2020). Secondary outcomes were (a) self-reported new SARS-CoV-2 infection at the study end-line and (b) self-reported symptomatic COVID-19 at baseline.

findingsPrevalence of high-risk alcohol consumption was 32 %. In models adjusted for demographics, students with high-risk alcohol consumption status had 2.44 [95% confidence interval (CI) = 1.35, 4.25] times the risk of SARS-CoV-2 seroconversion and 1.84 (95% CI = 1.04, 3.28) times the risk of self-reporting a positive SARS-CoV-2 infection, compared with students with no such risk. We did not identify any association between high-risk alcohol consumption and symptomatic COVID-19 (prevalence ratio = 1.17, 95% CI = 0.93, 1.47). Findings from sensitivity analyses corroborated these results and suggested potential for a dose-response relationship.

conclusionsAmong American college students, high-risk alcohol consumption appears to be associated with higher risk for severe acute respiratory syndrome coronavirus 2 seroconversion/infection.

Indexed as

AlcoholismCOVID-19Alcohol DrinkingCohort StudiesFemaleHumansMaleProspective StudiesSARS-CoV-2SeroconversionStudentsUnited StatesAmerican collegesAUDITAUDIT-CCOVID-19heavy drinkinghigh-risk alcohol consumptionquantity-frequency indexrespiratory diseaseSARS-CoV-2young adults

Identifiers

PMID35129232
PMCPMC9111375
OpenAlexW4210889693

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.