Evidence map›Paper›PMID 35129056›Full record

ArticleBioengineered2022

DNA methyltransferase 3 beta regulates promoter methylation of microRNA-149 to augment esophageal squamous cell carcinoma development through the ring finger protein 2/Wnt/β-catenin axis.

Junfeng Yang, Quan Zhang, Pu Zhao, Tong Qiao, Zhikun Cao, Fei Gao, Mengbo Liu, Sen Wu

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Bioengineered, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Frontiers in immunology · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 3 institutions in 1 country.

Junfeng YangDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Quan ZhangDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Pu ZhaoDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Tong QiaoDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Zhikun CaoDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Fei GaoDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Mengbo LiuDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Sen WuDepartment of Thoracic Surgery, Zhengzhou Key Laboratory of Surgical Treatment for End-stage Lung Diseases, Henan Provincial People's Hospital, People's Hospital of Zhengzhou University, Zhengzhou, P.R. China.
Henan Provincial People's Hospital · CNZhengzhou People's Hospital · CNZhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Esophageal squamous cell carcinoma (ESCC) is an aggressive form of human squamous cell carcinomas with extremely aggressive pathological features. This study explores the functions of microRNA-149 (

Indexed as

Esophageal NeoplasmsEsophageal Squamous Cell CarcinomaAdultAgedAnimalsbeta CateninCell Line, TumorDNA (Cytosine-5-)-MethyltransferasesDNA MethylationDNA Methyltransferase 3BHumansMiceMice, NudeMicroRNAsMiddle AgedPolycomb Repressive Complex 1beta CateninCTNNB1 protein, humanDNA (Cytosine-5-)-MethyltransferasesDNA Methyltransferase 3BMicroRNAsMIRN149 microRNA, humanPolycomb Repressive Complex 1RNF2 protein, humanWnt2 ProteinWNT2 protein, humanDNMT3BEsophageal squamous cell carcinomamethylationmiR-149RNF2wnt/β-catenin

Identifiers

PMID35129056
PMCPMC8973842
OpenAlexW4210252269

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.