Evidence map›Paper›PMID 35128939›Full record

ArticleJournal of aerosol medicine and pulmonary drug delivery2022

Lung Deposition of Inhaled Extrafine Beclomethasone Dipropionate/Formoterol Fumarate/Glycopyrronium Bromide in Healthy Volunteers and Asthma: The STORM Study.

Omar S Usmani, Simonetta Baldi, Simon Warren, Ilaria Panni, Luca Girardello, François Rony, Glyn Taylor, Wilfried DeBacker, George Georges

Registry-linked trialOpen access · hybridAbstract read
In one paragraph

Article in Journal of aerosol medicine and pulmonary drug delivery, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT03795350 (Open Label, Uncontrolled, Non-randomized, Single Dose, Scintigraphic Study to Investigate Lung Deposition of Inhaled 99mTc Radiolabelled TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients), which is not on this map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
6.7field-weighted citation impact, top 2% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT03795350 phase1terminatednot on this map

Open Label, Uncontrolled, Non-randomized, Single Dose, Scintigraphic Study to Investigate Lung Deposition of Inhaled 99mTc Radiolabelled TRIMBOW® pMDI in Healthy Volunteers, Asthmatic and COPD Patients

TypeinterventionalSponsorChiesi Farmaceutici S.p.A.Ran2019 to 2020Enrolled19ConditionsChronic Obstructive Pulmonary Disease, AsthmaArmsBeclometasone dipropionate Formoterol Fumarate Glycopyrronium Bromide
3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 47 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Small airways in asthma: Pathophysiology, identification and management.Chinese medical journal pulmonary and critical care medicine · 2023
    Review
  13. Article
  14. Review
  15. Article
  16. Review
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 3 countries.

Omar S UsmaniNHLI Imperial College London, London, United Kingdom.
Simonetta BaldiChiesi Farmaceutici SpA, Parma, Italy.
Simon WarrenCardiff Scintigraphics Ltd., Cardiff, United Kingdom.
Ilaria PanniChiesi Farmaceutici SpA, Parma, Italy.
Luca GirardelloCROS NT Srl, Verona, Italy.
François RonyChiesi Farmaceutici SpA, Parma, Italy.
Glyn TaylorCardiff Scintigraphics Ltd., Cardiff, United Kingdom.
Wilfried DeBackerDepartment of Respiratory Medicine, University of Antwerp, Antwerpen, Belgium.
George GeorgesChiesi Farmaceutici SpA, Parma, Italy.ORCID 0000-0002-0303-2273
Chiesi (Italy) · ITCardiff University · GBImperial College London · GBUniversity of Antwerp · BEUniversity of Verona · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

AsthmaBeclomethasoneAdministration, InhalationDrug CombinationsFormoterol FumarateGlycopyrrolateHealthy VolunteersHumansLungTreatment OutcomeBeclomethasoneDrug CombinationsFormoterol FumarateGlycopyrrolatelung depositionperipheral airwaysradiolabelingscintigraphytriple therapy

Identifiers

PMID35128939
PMCPMC9416540
OpenAlexW4210892673

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.