Evidence map›Paper›PMID 35128663›Full record

ArticleInternational journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics2022

The impact of COVID-19 vaccine on sperm quality.

Shimi Barda, Ido Laskov, Dan Grisaru, Ofer Lehavi, Sandra Kleiman, Atalia Wenkert, Foad Azem, Ron Hauser, Nadav Michaan

Open access · greenAbstract read
In one paragraph

Article in International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 5 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
18citing papers in PubMed, 5 pooled it
6.3field-weighted citation impact, top 3% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

18 citing papers in PubMed, 5 syntheses or guidelines pooled it, 35 citations in OpenAlex.

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  12. SARS-CoV-2, fertility and assisted reproduction.Human reproduction update · 2023
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  18. The impact of COVID-19 vaccine on sperm quality.International journal of gynaecology and obstetrics: the official organ of the International Federation of Gynaecology and Obstetrics · 2022
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 1 institution in 1 country.

Shimi BardaThe Institute for the Study of Fertility, Tel Aviv University, Tel Aviv, Israel.
Ido LaskovGynecologic Oncology Department, Tel Aviv University, Tel Aviv, Israel.
Dan GrisaruGynecologic Oncology Department, Tel Aviv University, Tel Aviv, Israel.
Ofer LehaviThe Institute for the Study of Fertility, Tel Aviv University, Tel Aviv, Israel.
Sandra KleimanThe Institute for the Study of Fertility, Tel Aviv University, Tel Aviv, Israel.
Atalia WenkertGynecologic Oncology Department, Tel Aviv University, Tel Aviv, Israel.
Foad AzemRacine IVF Unit, Lis Maternity Hospital, Tel Aviv Sourasky Medical Center, Sackler School of Medicine, Tel Aviv University, Tel Aviv, Israel.
Ron HauserThe Institute for the Study of Fertility, Tel Aviv University, Tel Aviv, Israel.
Nadav MichaanGynecologic Oncology Department, Tel Aviv University, Tel Aviv, Israel.
Tel Aviv University · IL

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveTo examine the effect of the BNT162b, mRNA, SARS-CoV-2 virus vaccine on sperm quality.

methodsThis was a prospective cohort study conducted on sperm donors at the sperm bank of a tertiary, university affiliated medical center. All sperm donors donated sperm repeatedly and the average sperm parameters of all available samples were compared before and after receiving the SARS-CoV-2 vaccine. Each donor served as his own control. For all participants, at-least one sperm sample was received 72 days after completing the second vaccine. Main outcome measures included total sperm count, total motile count and percent of motile sperm.

resultsA total of 898 sperm samples from 33 sperm donors that were vaccinated with the Pfizer BNT162b, mRNA, SARS-CoV-2 virus vaccine were analyzed, 425 samples were received before the vaccine, while 473 samples were received after vaccination. Total sperm count and total motile count increased after the second vaccine compared to samples before vaccination. Percent of motile sperm did not change after vaccine.

conclusionThe Pfizer BNT162b, SARS-CoV-2 vaccine has no deleterious effect on sperm quality. Patients and physicians should be counseled accordingly.

Indexed as

COVID-19Sperm MotilityCOVID-19 VaccinesHumansMaleProspective StudiesRNA, MessengerSARS-CoV-2SpermatozoaCOVID-19 VaccinesRNA, MessengerCOVID-19sperm countsperm quality vaccine

Identifiers

PMID35128663
PMCPMC9087610
OpenAlexW4210854656

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.