ArticleClinical rheumatology2022
Clinical characteristics and radiographic outcomes of vascular Behçet's disease involving the aorta or its major branches.
Article in Clinical rheumatology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
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Who cites it
5 citing papers in PubMed, 5 citations in OpenAlex.
- Correlation analysis of cytokine levels and peripheral blood T lymphocyte subsets in systemic vascular inflammatory disease.Journal of medical biochemistry · 2026Article
- Non-pulmonary arterial involvement in Behçet's disease: a multicenter retrospective case series.Turkish journal of medical sciences · 2026Observational
- Clinical characteristics, treatment, and prognosis of pediatric Vasculo-Behçet's syndrome: a retrospective analysis of 12 cases.Frontiers in pediatrics · 2026Article
- Severe aortic regurgitation with acute decompensation as initial presentation of Behçet's syndrome: a case report.European heart journal. Case reports · 2025Article
- A Case Report of Behcet's Disease With Thromboses in the Superior Vena Cava and External Iliac Vein.Cureus · 2022Article
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Authors and funding
8 authors at 1 institution in 1 country.
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Abstract
objectiveTo describe the clinical characteristics and radiographic outcomes of vascular Behçet's disease (BD) involving the aorta or its major branches.
methodsThis retrospective cohort study was performed in patients with vascular BD involving the aorta or its major branches. All included patients underwent computed tomography angiography (CTA) at least two times with a 2- to 5-year interval. Radiographic progression was defined as newly developed and/or aggravated (> 20%) characteristic features on CTA.
resultsThe cohort included 22 patients with BD with a median interval of 3.65 years between the initial and follow-up CTA. Five patients (22.7%) showed radiographic progression. Patients with radiographic progression had a longer disease duration at baseline than those without (6.67 vs. 0.26 years, p = 0.028). Of all patients, 21 (95.5%) had vascular aneurysms/pseudoaneurysms and 11 (50.0%) had thrombosis. The most frequently involved artery with aneurysmal change was the abdominal aorta (8/21, 38.1%), followed by the iliac arteries (5/21, 23.8%). In the case of thrombosis, the most frequently involved arteries were the femoral (4/11, 36.4%) and iliac (4/11, 36.4%) arteries. The characteristics and locations of vascular involvement did not significantly differ according to the radiographic outcome.
conclusionsA considerable proportion of patients with BD with arterial involvement showed radiographic progression within 2-5 years. Patients with radiographic progression had a longer disease duration at baseline. The most common form of arterial involvement of BD was aneurysmal change, followed by thrombus formation. KEY POINTS: • This study evaluated for the first time the radiographic outcomes of 22 patients with Behçet's disease involving the aorta or its major branches. • A considerable proportion of patients (5/22, 22.7%) showed radiographic progression. • Patients with radiographic progression had a longer disease duration at baseline than their counterparts; however, no other clinical factors were significantly different. • The most frequent form of vascular involvement was pseudoaneurysm followed by thrombosis.
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