Evidence map›Paper›PMID 35128582›Full record

ArticleEuropean journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology2022

Assessing the diagnostic accuracy of the Xpert MTB/RIF assay in detecting epididymal tuberculosis.

Pengju Liu, Yuan Liu, Yeqiang Wang, Sida Hao, Yong Qin

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Article in European journal of clinical microbiology & infectious diseases : official publication of the European Society of Clinical Microbiology, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
1.1field-weighted citation impact, top 25% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 5 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Pengju LiuDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Yuan LiuDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Yeqiang WangDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Sida HaoDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China.
Yong QinDepartment of Urology, Affiliated Hangzhou Chest Hospital, Zhejiang University School of Medicine, 208 East Huancheng Road, Hangzhou, China. hhyyqinyong@163.com.
Second Affiliated Hospital of Zhejiang University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

To assess the diagnostic efficacy of Xpert MTB/RIF assay in detecting epididymal tuberculosis.

methodsWe analyzed 84 samples from patients with suspected epididymal TB or chronic epididymitis who received surgical treatment (epididymal resection or epididymis-testicular resection) at our hospital between July 1, 2016 and July 1, 2020. A composite reference standard (CRS) was used in this study. We determined the sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and area under the curve (AUC) of the Xpert MTB/RIF assay for epididymal TB and compared its diagnostic accuracy with that of the Mycobacterium tuberculosis (MTB) culture test in detecting epididymal TB.

resultsThree patients were excluded because of incomplete data. Comparing with the composite reference standard, the sensitivity, specificity, PPV, NPV, and AUC of Xpert MTB/RIF assay for epididymal TB were 80.95% (69.09-89.75%); 94.44% (72.71-99.86%); 98.08% (89.74-99.95%); and 58.62% (38.94-76.48%), respectively, with an AUC of 0.88 (95% confidence interval: 0.79-0.94). The diagnostic sensitivity of the Xpert MTB/RIF assay was significantly higher than that of the MTB culture test for epididymal TB.

conclusionsWe recommend the Xpert MTB/RIF assay as a diagnostic method for the detection of epididymal TB.

Indexed as

Mycobacterium tuberculosisTuberculosisEpididymisHumansMalePredictive Value of TestsSensitivity and SpecificitySputumDiagnostic methodEpididymal tuberculosisMycobacterium tuberculosis cultureXpert MTB/RIF assay

Identifiers

PMID35128582
OpenAlexW4210658891

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.