Evidence map›Paper›PMID 35128573›Full record

ArticleArchives of pharmacal research2022

Enhancing solubility and bioavailability of coenzyme Q

Shrawani Lamichhane, Jo-Eun Seo, Taekwang Keum, Gyubin Noh, Santosh Bashyal, Seong-Wan Cho, Eun-Hee Lee, Sangkil Lee

Abstract read
PubMed Publisher
In one paragraph

Article in Archives of pharmacal research, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed, 1 pooled it
1.0field-weighted citation impact, top 26% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Optimized CoQ10 deliveryRSC advances · 2026
    Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 2 institutions in 1 country.

Shrawani LamichhaneCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea.
Jo-Eun SeoCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea.
Taekwang KeumCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea.
Gyubin NohCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea.
Santosh BashyalCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea.
Seong-Wan ChoDepartment of Pharmaceutics & Biotechnology, 158, Gwanjeodong-ro, Seo-gu, Daejeon, 35365, Republic of Korea.
Eun-Hee LeeDepartment of Pharmacy, Korea University, 2511 Sejong-ro, Sejong, 30019, Republic of Korea.
Sangkil LeeCollege of Pharmacy, Keimyung University, 1095 Dalgubeol-daero, Dalseo-gu, Daegu, 42601, Republic of Korea. skdavid@kmu.ac.kr.
Keimyung University · KRKorea University · KR

Funding

College of Pharmacy, Keimyung University 2017
6 · The paper itself

Abstract

Improving the aqueous solubility of poorly soluble compounds have been a major issue in the pharmaceutical industry. In the present study, binary amorphous solid dispersions (SDs) of Coenzyme Q10 (CoQ

Indexed as

Administration, OralAnimalsBiological AvailabilityCalorimetry, Differential ScanningMaleMicroscopy, Electron, ScanningPolyethylene GlycolsPolyvinylsRatsRats, Sprague-DawleySolubilitySpectroscopy, Fourier Transform InfraredUbiquinoneX-Ray Diffractioncoenzyme Q10Polyethylene Glycolspolyvinyl caprolactam-polyvinyl acetate-polyethylene glycol graft copolymerPolyvinylsUbiquinoneBioavailabilityCoenzyme Q10Solid dispersionSolubilitySoluplus®

Identifiers

PMID35128573
OpenAlexW4210341952

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.