Evidence map›Paper›PMID 35128509›Full record

ArticleCell genomics2021

International federation of genomic medicine databases using GA4GH standards.

Adrian Thorogood, Heidi L Rehm, Peter Goodhand, Angela J H Page, Yann Joly, Michael Baudis, Jordi Rambla, Arcadi Navarro, Tommi H Nyronen, Mikael Linden and 5 more

Abstract read
In one paragraph

Article in Cell genomics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Adrian ThorogoodELIXIR-Luxembourg and Biocore, Luxembourg Centre for Systems Biomedicine, University of Luxembourg, Belvaux, Luxembourg.
Heidi L RehmCenter for Genomic Medicine, Massachusetts General Hospital, Boston, MA, USA.
Peter GoodhandGlobal Alliance for Genomics and Health, Toronto, ON, Canada.
Angela J H PageBroad Institute of MIT and Harvard, Cambridge, MA, USA.
Yann JolyCentre of Genomics and Policy, Department of Human Genetics, McGill University, Montreal, QC, Canada.
Michael BaudisUniversity of Zurich and Swiss Institute of Bioinformatics, Zurich, Switzerland.
Jordi RamblaCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Arcadi NavarroCentre for Genomic Regulation (CRG), The Barcelona Institute of Science and Technology, Barcelona, Spain.
Tommi H NyronenCSC - IT Center for Science, Life Science Center, Espoo, Finland.
Mikael LindenCSC - IT Center for Science, Life Science Center, Espoo, Finland.
Edward S DoveSchool of Law, University of Edinburgh, Edinburgh, UK.
Marc FiumeDNAstack, Toronto, ON, Canada.
Michael BrudnoDepartment of Computer Science, University of Toronto and University Health Network, Toronto, ON, Canada.
Melissa S ClineUC Santa Cruz Genomics Institute, Mail Stop: Genomics, 1156 High Street, Santa Cruz, CA 95064, USA.
Ewan BimeyEuropean Molecular Biology Laboratory, European Bioinformatics Institute, Wellcome Genome Campus, Cambridgeshire, UK.

Funding

Resource ProjectU41HG006834 · NHGRI · BRIGHAM AND WOMEN'S HOSPITAL · PI REHM, HEIDI L · 2013 to 2020
$26.9M
Training SubprojectU54HG007990 · NHGRI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI HAUSSLER, DAVID H, PATTERSON, DAVID · 2014 to 2018
$14.8M
Tracking Ethical Provenance for Sharing Genomic and Health Related DataU24HG011025 · NHGRI · BROAD INSTITUTE, INC. · PI HEIDI L REHM · 2021 to 2026
$8.2M
Federated Analysis in Cancer Genomics: Surveying the Social, Ethical, and Regulatory LandscapeU01CA242954 · NCI · UNIVERSITY OF CALIFORNIA SANTA CRUZ · PI CLINE, MELISSA SUZANNE · 2019 to 2021
$1.5M
Medical Research Council MC_PC_19024NCI NIH HHS U01 CA242954NHGRI NIH HHS U24 HG011025NHGRI NIH HHS U41 HG006834NHGRI NIH HHS U54 HG007990Wellcome Trust
6 · The paper itself

Abstract

We promote a shared vision and guide for how and when to federate genomic and health-related data sharing, enabling connections and insights across independent, secure databases. The GA4GH encourages a federated approach wherein data providers have the mandate and resources to share, but where data cannot move for legal or technical reasons. We recommend a federated approach to connect national genomics initiatives into a global network and precision medicine resource.

Identifiers

PMID35128509
PMCPMC8813094

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.