Evidence map›Paper›PMID 35128281›Full record

ArticleACS omega2022

A Fresh Look at the Potential of Cyclodextrins for Improving the Delivery of siRNA Encapsulated in Liposome Nanocarriers.

Betzaida Castillo Cruz, Marienid Flores Colón, Robert J Rabelo Fernandez, Pablo E Vivas-Mejia, Gabriel L Barletta

Abstract read
In one paragraph

Article in ACS omega, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Delivery Strategies of siRNA Therapeutics for Hair Loss Therapy.International journal of molecular sciences · 2024
    Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Betzaida Castillo CruzDepartment of Chemistry, University of Puerto Rico, Humacao Campus, Humacao 00791, Puerto Rico.
Marienid Flores ColónUPR Comprehensive Cancer Center, Medical Center Area, Ave. José Celso Barbosa, San Juan 00935, Puerto Rico.
Robert J Rabelo FernandezUPR Comprehensive Cancer Center, Medical Center Area, Ave. José Celso Barbosa, San Juan 00935, Puerto Rico.
Pablo E Vivas-MejiaUPR Comprehensive Cancer Center, Medical Center Area, Ave. José Celso Barbosa, San Juan 00935, Puerto Rico.
Gabriel L BarlettaDepartment of Chemistry, University of Puerto Rico, Humacao Campus, Humacao 00791, Puerto Rico.ORCID https://orcid.org/0000-0003-0016-901X

Funding

Upstream Regulation and Downstream effectors of c-MYC in Ovarian CancerU54MD007600 · NIMHD · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI Emma Fernandez-Repollet · 2017 to 2026
$35.8M
Upgrade Laboratories Facilities at UPR-Rio PiedrasR25GM061151 · NIGMS · UNIVERSITY OF PUERTO RICO RIO PIEDRAS · PI CARBALLEIRA, NESTOR MANUEL · 2001 to 2023
$32.5M
RISE Option III: MBRS RISE at the UPR Medical Sciences CampusR25GM061838 · NIGMS · UNIVERSITY OF PUERTO RICO MED SCIENCES · PI CADILLA, CARMEN LYDIA · 2000 to 2021
$25.5M
Novel Gold nanocarriers conjugates for microRNA delivery in ovarian cancerSC3GM122622 · NIGMS · UNIVERSITY OF PUERTO RICO AT HUMACAO · PI BARLETTA, GABRIEL LUIS · 2018 to 2021
$379k
NIGMS NIH HHS R25 GM061151NIGMS NIH HHS R25 GM061838NIGMS NIH HHS SC3 GM122622NIMHD NIH HHS U54 MD007600
6 · The paper itself

Abstract

Liposomes are among the most effective vehicles to deliver siRNAs to cells, both

Identifiers

PMID35128281
PMCPMC8812098

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.