Evidence map›Paper›PMID 35128225›Full record

ArticleClinical research (Milpitas, Calif.)2020

Investigation of Bladder Cancer Cell Response to Cryoablation and Adjunctive Cisplatin Based Cryo/Chemotherapy.

Kimberly L Santucci, John M Baust, Kristi K Snyder, Robert G Van Buskirk, Aaron Katz, Anthony Corcoran, John G Baust

Open access · diamondAbstract read
In one paragraph

Article in Clinical research (Milpitas, Calif.), 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
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  3. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Kimberly L SantucciCPSI Biotech, Owego, USA.
John M BaustCPSI Biotech, Owego, USA.
Kristi K SnyderCPSI Biotech, Owego, USA.
Robert G Van BuskirkCPSI Biotech, Owego, USA.
Aaron KatzDepartment of Urology, NYU Winthrop Hospital, US.
Anthony CorcoranDepartment of Urology, NYU Winthrop Hospital, US.
John G BaustCenter for Translational Stem Cell and Tissue Engineering Binghamton University, USA.
Cell Preservation Services (United States) · USBinghamton University · USWinthrop-University Hospital · US

Funding

FrostBite-BC - A New Thermal Ablation Device for Treating Bladder CancerR43CA210761 · NCI · CELL PRESERVATION SERVICES, INC. · PI BAUST, JOHN M · 2017 to 2017
$309k
NCI NIH HHS R43 CA210761
6 · The paper itself

Abstract

Due to a rising annual incidence of bladder cancer, there is a growing need for development of new strategies for treatment. In 2018, the World Cancer Research Fund and other groups reported that there were ~550,000 new cases worldwide of bladder cancer. It has been further estimated that >200,000 individuals die annually from bladder cancer worldwide. Various treatment options exist. However, many if not all remain suboptimal. While the preferred chemotherapeutic options have changed in the past few years there have been few advances in the bladder cancer medical device field. Cryoablation is now being evaluated as a new option for the treatment of bladder cancer. While several studies have shown cryoablation to be promising for the treatment of bladder cancer, a lack of basic information pertaining to dosing (minimal lethal temperature) necessary to destroy bladder cancer has limited its use as a primary therapeutic option. Concerns with bladder wall perforation and other side effects have also slowed adoption. In an effort to detail the effects of freezing on bladder cancer, two human bladder cancer cell lines, SCaBER and UMUC3, were evaluated

Identifiers

PMID35128225
PMCPMC8813088
OpenAlexW3015272274

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.