ArticleAmerican journal of ophthalmology case reports2022
Macular pucker formation after inverted internal limiting membrane flap technique: Two case reports.
Article in American journal of ophthalmology case reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.
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Who cites it
10 citing papers in PubMed, 18 citations in OpenAlex.
- Current Approaches in the Management of Complicated Macular Holes.Turkish journal of ophthalmology · 2026Review
- Characteristics and surgical outcomes of combat blast-related full-thickness traumatic macular holes: insights from war eye trauma in Ukraine.International journal of retina and vitreous · 2026Article
- Development of secondary epiretinal membrane after vitrectomy with inverted ILM flap technique to treat a macular hole.American journal of ophthalmology case reports · 2025Article
- Comparison of ILM peeling vs. inverted ILM flap for macular hole closure and visual outcomes: systematic review and meta-analysis.International journal of retina and vitreous · 2025Review
- Development of a prognostic surgical index using optical coherence tomography for large macular holes: a retrospective multicenter study.BMC ophthalmology · 2025Article
- Proliferative gliosis, a rare finding following multilayered inverted internal limiting membrane flap technique for concurrent macular hole and retinal detachment: Case series.American journal of ophthalmology case reports · 2024Article
- Flap-Related Complications Following Temporal Inverted Internal Limiting Membrane Flap for Macular Hole Repair.Turkish journal of ophthalmology · 2023Article
- Short-Term Clinical Results After ILM Removal and Inverted ILM Flap for Macular Hole Repair - A Single-Center Retrospective Experience.Clinical ophthalmology (Auckland, N.Z.) · 2023Article
- Glial-Plug Proliferation after Inverted Internal Limiting Membrane Flap Technique for Idiopathic Macular Hole.Journal of ophthalmology · 2022Article
- Visual Improvement Despite Macular Pucker After Inverted Internal Limiting Membrane Flap Technique for Idiopathic Macular Hole.Journal of vitreoretinal diseasesArticle
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Authors and funding
3 authors at 1 institution in 1 country.
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No grant is acknowledged in the PubMed record.
Abstract
purposeThe inverted internal limiting membrane (ILM) flap technique is generally used to treat refractory macular holes (MHs). Recently, a case of macular pucker formation outside the ILM flap after using silicone oil was reported. Although the pucker formation was attributed to the silicone oil use in that case, here we report two cases of macular pucker that occurred after the inverted ILM flap technique was performed without silicone oil. In one case, the ILM flap and proliferated tissue was removed, followed by their histopathological examination. OBSERVATIONS: Two patients with MH underwent vitrectomies using the inverted ILM flap technique. In both patients, the visual acuity worsened postoperatively, and macular pucker formation, associated with the ILM flap, was observed. In one patient, visual acuity improved after ILM flap removal, and histopathological examination of the specimen indicated strong cellular proliferation between the ILMs. CONCLUSIONS AND IMPORTANCE: Following the inverted ILM flap technique, macular pucker may occur even without the use of silicone oil. Removal of the flap and associated proliferative tissue was effective and resulted in no recurrence of MH or pucker. Ophthalmologists should consider the possibility that tissues on the ILM may lead to macular pucker formation especially inside the flap, in the area between the ILMs.
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