Evidence map›Paper›PMID 35128119›Full record

ArticleJournal of spine surgery (Hong Kong)2021

Is there consensus on the perioperative management of Xa inhibitors in patients undergoing elective spine surgery?-A survey of current spine surgeon practices.

Ashley E Xiong, Taylor J Jackson, Bryan Kinsey Lawson, Navid Khezri, Arjun Sebastian, Brett Freedman, Benjamin Elder, Bradford Currier

Open access · diamondAbstract read
In one paragraph

Article in Journal of spine surgery (Hong Kong), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
0.2field-weighted citation impact, top 44% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 1 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Ashley E XiongDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Taylor J JacksonDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Bryan Kinsey LawsonDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Navid KhezriDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Arjun SebastianDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Brett FreedmanDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Benjamin ElderDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Bradford CurrierDepartment of Orthopedic Surgery, Mayo Clinic, Rochester, MN, USA.
Mayo Clinic in Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFactor Xa inhibitors (Xai) are an increasingly common consideration in perioperative anticoagulation management. However, there no existing guidelines established for use in Spine Surgery. This survey study aims to capture current practice trends regarding the perioperative management of Xai among spine surgeons.

methodsAn 11-question survey was sent to all surgeon members of 3 spinal surgery societies. Responses were remitted anonymously. Questions characterized the background and experience of the respondent and inquired into their current perioperative Xai and other anticoagulant management. Questions were all single-best option, multiple-choice.

resultsA total of 116 surveys were received. Twenty-six (22.4%) were from neurosurgeons and 90 (77.6%) were from orthopedic surgeons. Practiced preoperative Xai hold length tended to be longer than recommended by the respondent's medical colleagues. Only 65.2% (P≤0.0001) of respondents practiced in agreement with the recommendations of their medical colleagues. Postoperative Xai holds trended toward longer holds than that of other anticoagulants with 37.9% (P=0.0125) of respondents showed differences within their own practice between length of Xai hold and length of other anticoagulant holds. One out of four respondents reported noticing a change in the rate of perioperative bleeding complications among Xai patients. Despite reported increased bleeding issues, only 39% of those who noted this increase in bleeding complications reported they would hold a Xai longer than other anticoagulants.

conclusionsThere exists a wide range of recommended and practiced chronic anticoagulant hold lengths. This inconsistency likely highlights conflicting risk aversion among surgeons, between complications which are viewed as medical (i.e., thromboembolism and stroke) KEYWORDS: Anticoagulants; factor Xa inhibitors (factor Xai); spine; orthopedic surgery; neurosurgery.

Identifiers

PMID35128119
PMCPMC8743296
OpenAlexW4200043815

What OpenQuestion holds

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Read underepoch 390

Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.