ArticleBiochemistry and biophysics reports2022
The aqueous humor proteome is intrinsically disordered.
Article in Biochemistry and biophysics reports, 2022. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
7 citing papers in PubMed, 8 citations in OpenAlex.
- Bioinformatics-Based Comparative Analysis of the Human Retina Proteome.Proteomics. Clinical applications · 2025Article
- The effects of retinal disease on intrinsic protein disorder and liquid-liquid‑phase separation.Journal of proteins and proteomics · 2025Article
- An Analysis of Intrinsic Protein Disorder in Antimicrobial Peptides.The protein journal · 2025Article
- Effects of Aging on Intrinsic Protein Disorder in Human Lenses and Zonules.Cell biochemistry and biophysics · 2024Article
- Effects of Aging on Intrinsic Protein Disorder in Human Lenses and Zonules.Cell biochemistry and biophysics · 2024Article
- Intrinsic disorder in the human vitreous proteome.International journal of biological macromolecules · 2024Article
- Intrinsic Disorder in the Human Tear Proteome.Investigative ophthalmology & visual science · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
•Our study demonstrated that intrinsic disorder is abundant in the aqueous humor.•The 749 aqueous proteins analyzed were enriched with disorder-promoting residues.•208 aqueous humor proteins were predicted to be highly intrinsically disordered.•Misregulation of IDPs may promote pathology in the aqueous humor.•IDPs in aqueous humor may serve as future targets for novel therapeutics.
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.