Evidence map›Paper›PMID 35127885›Full record

ArticleFrontiers in veterinary science2021

The Role of Tea Tree Oil in Alleviating Palmitic Acid-Induced Lipid Accumulation in Bovine Hepatocytes.

Tianyu Yang, Xiaoyu Ma, Maocheng Jiang, Zhiqiang Cheng, Osmond Datsomor, Guoqi Zhao, Kang Zhan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
2.8field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it, 13 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Tianyu YangInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Xiaoyu MaInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Maocheng JiangInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Zhiqiang ChengInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Osmond DatsomorInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Guoqi ZhaoInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Kang ZhanInstitute of Animal Culture Collection and Application, College of Animal Science and Technology, Yangzhou University, Yangzhou, China.
Yangzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Tea tree oil (TTO) plays an important role in lipid metabolism, alleviating the inflammatory responses. Fatty liver is associated with lipid accumulation in hepatocytes, leading to inflammation. However, there is very limited information on the effects of TTO on lipid accumulation, and inflammation in bovine hepatocytes. This study aimed to evaluate whether TTO alleviates palmitic acid (PA)-induced lipid accumulation in bovine hepatocytes. Hepatocytes isolated from mid-lactating Holstein cows were pretreated with 100 μM PA for 72 h. Cells were either pretreated with PA alone (PA group) or with PA followed by 0.00625% TTO treatment for 12 h (PT group). Expression of fatty acid oxidant genes increased (

Indexed as

bovine hepatocytesendoplasmic reticulum stressfatty acid metabolisminflammationtea tree oil

Identifiers

PMID35127885
PMCPMC8814581
OpenAlexW4206960173

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.