Evidence map›Paper›PMID 35127861›Full record

SynthesisFrontiers in cardiovascular medicine2021

The Prevalence and Associated Death of Ventricular Arrhythmia and Sudden Cardiac Death in Hospitalized Patients With COVID-19: A Systematic Review and Meta-Analysis.

Ziqi Tan, Shan Huang, Kaibo Mei, Menglu Liu, Jianyong Ma, Yuan Jiang, Wengen Zhu, Peng Yu, Xiao Liu

Open access · goldAbstract readSystematic Review
In one paragraph

Synthesis in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed, 3 pooled it
2.4field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 3 syntheses or guidelines pooled it, 24 citations in OpenAlex.

  1. Pooled it
  2. Pooled it
  3. Pooled it
  4. Observational
  5. Article
  6. Review
  7. Article
  8. Article
  9. Article
  10. Protein 14-3-3 Influences the Response of the Cardiac Sodium Channel NaThe Journal of pharmacology and experimental therapeutics · 2023
    Article
  11. Sudden cardiac death in the adolescent population: a narrative review.The Egyptian journal of internal medicine · 2023
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 8 institutions in 2 countries.

Ziqi TanDepartment of Endocrine, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Shan HuangDepartment of Psychiatry, The Third People's Hospital of Ganzhou, Ganzhou, China.
Kaibo MeiDepartment of Anesthesiology, The People's Hospital of Shangrao, Shangrao, China.
Menglu LiuDepartment of Cardiology, The Seventh People's Hospital of Zhengzhou, Zhengzhou, China.
Jianyong MaDepartment of Pharmacology and Systems Physiology, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Yuan JiangDepartment of Pharmacy, Harbin Medical University, Harbin, China.
Wengen ZhuDepartment of Cardiology, The First Affiliated Hospital of Sun Yat-sen University, Guangzhou, China.
Peng YuDepartment of Endocrine, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Xiao LiuDepartment of Cardiology, The Second Affiliated Hospital of Nanchang University, Nanchang, China.
Nanchang University · CNGanzhou People's Hospital · CNHarbin Medical University · CNSecond Affiliated Hospital of Nanchang University · CNShangrao Normal University · CNSun Yat-sen University · CNUniversity of Cincinnati Medical Center · USZhengzhou People's Hospital · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArrhythmia is a very common complication of coronavirus disease 2019 (COVID-19); however, the prevalence of ventricular arrhythmia and associated outcomes are not well-explored. Here, we conducted a systematic review and meta-analysis to determine the prevalence and associated death of ventricular arrhythmia and sudden cardiac death (SCD) in patients with COVID-19.

methodsDatabases of PubMed, Cochrane Library, Embase, and MdeRxiv were searched. Studies that could calculate the prevalence of ventricular arrhythmia/SCD during hospital admission or associated death in patients with COVID-19 were included. The study was registered with the PROSPERO (CRD42021271328).

resultsA total of 21 studies with 13,790 patients were included. The pooled prevalence of ventricular arrhythmia was 5% (95% CI: 4-6%), with a relatively high-SCD prevalence (1.8% in hospitalized COVID-19 and 10% in deceased cases of COVID-19). Subgroup analysis showed that ventricular arrhythmia was more common in patients with elevated cardiac troponin T [ES (effect size): 10%, 95% CI: -0.2 to 22%] and in European (ES: 20%, 95% CI: 11-29%) populations. Besides, ventricular arrhythmia was independently associated with an increased risk of death in patients with COVID-19 [odds ratio (OR) = 2.83; 95% CI: 1.78-4.51].

conclusionVentricular arrhythmia and SCD resulted as a common occurrence with a high prevalence in patients with COVID-19 admitted to the hospital. Furthermore, ventricular arrhythmia significantly contributed to an increased risk of death in hospitalized patients with COVID-19. Clinicians might be vigilant of ventricular arrhythmias for patients with COVID-19, especially for severe cases. SYSTEMATIC REVIEW REGISTRATION: www.york.ac.uk/inst/crd, identifier: CRD42021271328.

Indexed as

arrhythmiacoronavirus disease 2019deathprevalenceprognosisventricular arrhythmia

Identifiers

PMID35127861
PMCPMC8814312
OpenAlexW4206018108

What OpenQuestion holds

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LicenceCC BY
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.