Evidence map›Paper›PMID 35127784›Full record

ArticleFrontiers in nutrition2021

Prognostic Significance of Modified Advanced Lung Cancer Inflammation Index in Patients With Renal Cell Carcinoma Undergoing Laparoscopic Nephrectomy: A Multi-Institutional, Propensity Score Matching Cohort Study.

Weipu Mao, Keyi Wang, Yuan Wu, Jinliang Ni, Houliang Zhang, Yidi Wang, Zonglin Wu, Ruiji Liu, Jiang Geng, Shuqiu Chen and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.3field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 12 citations in OpenAlex.

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  8. Frontiers in oncology · 2022
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 1 country.

Weipu MaoDepartment of Urology, Shidong Hospital of Yangpu District, Shanghai, China.
Keyi WangDepartment of Urology, Shidong Hospital of Yangpu District, Shanghai, China.
Yuan WuDepartment of Urology, Hefei Cancer Hospital, Chinese Academy of Sciences, Hefei, China.
Jinliang NiDepartment of Urology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Houliang ZhangDepartment of Urology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Yidi WangDepartment of Urology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Zonglin WuDepartment of Urology, Shidong Hospital of Yangpu District, Shanghai, China.
Ruiji LiuDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.
Jiang GengDepartment of Urology, School of Medicine, Shanghai Tenth People's Hospital, Tongji University, Shanghai, China.
Shuqiu ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.
Ming ChenDepartment of Urology, Affiliated Zhongda Hospital of Southeast University, Nanjing, China.
Zhongda Hospital Southeast University · CNShanghai Tenth People's Hospital · CNHefei Institutes of Physical Science · CNTongji University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundWe conducted a multi-institutional clinical study to assess the prognostic value of the advanced lung cancer inflammatory index (ALI) and modified ALI (mALI) in patients with renal cell carcinoma (RCC).

methodsWe collected 440 patients who underwent laparoscopic nephrectomy at three centers from 2014 to 2019. ALI was defined as body mass index (BMI) × serum albumin (ALB)/neutrophil-to-lymphocyte ratio (NLR) and mALI as L3 muscle index × ALB/NLR. Kaplan-Meier curves, receiver operating characteristic (ROC) curves and Cox survival analysis were used to assess the effect of ALI and mALI on overall survival (OS). In addition, we performed 1:1 propensity score matching (PSM) for the high mALI and low mALI groups to further explore the impact of mALI on survival in RCC patients.

resultsThe optimal cut-off values for ALI and mALI were 40.6 and 83.0, respectively. Based on the cut-off values, we divided the patients into high ALI and low ALI groups, high mALI and low mALI groups. ALI and mALI were significantly associated with the AJCC stage, Fuhrman grade, T stage, and M stage. Low ALI (

conclusionsFor RCC patients undergoing laparoscopic nephrectomy, low ALI and low mALI were associated with poor prognosis, and preoperative mALI can be used as a potential independent prognostic indicator for RCC patients.

Indexed as

advanced lung cancer inflammatory indexbiomarkermodified advanced lung cancer inflammatory indexoverall survivalrenal cell carcinoma

Identifiers

PMID35127784
PMCPMC8811296
OpenAlexW4226040305

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.